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Autor:
Roshni Saravanan, Vaishnavi Balasubramanian, Srikanth Swamy Swaroop Balamurugan, Inemai Ezhil, Zeba Afnaan, Jisha John, Sandhya Sundaram, Shanmugasundaram Gouthaman, Suresh B. Pakala, Suresh Kumar Rayala, Ganesh Venkatraman
Publikováno v:
Journal of Cellular Physiology. 237:4132-4156
Breast cancer is one of the leading causes contributing to the global cancer burden. The triple negative breast cancer (TNBC) molecular subtype accounts for the most aggressive type. Despite progression in therapeutic options and prognosis in breast
Autor:
Pei‐Feng Liu, Chun‐Feng Chen, Luo‐Ping Ger, Wei‐Lun Tsai, Ho‐Hsing Tseng, Cheng‐Hsin Lee, Wen‐Hsin Yang, Chih‐Wen Shu
Publikováno v:
Journal of Cellular Physiology. 237:4275-4291
Autophagy-related 4B (ATG4B) is a protease required for core machinery of autophagy. Phosphorylation of ATG4B promotes autophagy and is correlated with poor outcome of cancer. However, little is known about the upstream kinases for ATG4B phosphorylat
Autor:
Heeseung Oh, Seung Yeon Park, Wonjun Cho, A. M. Abd El‐Aty, Ahmet Hacimuftuoglu, Chang Hyuk Kwon, Ji Hoon Jeong, Tae Woo Jung
Publikováno v:
Journal of Cellular Physiology. 237:4226-4237
Recently, sclerostin (SCL), a circulating glycoprotein, was proposed to be a novel myokine involved in developing metabolic disorders. The association between SCL levels and insulin resistance in skeletal muscle, liver, and adipose tissue was studied
Publikováno v:
Journal of Cellular Physiology. 237:3975-3983
Primary cilia, microtubule-based protrusions present on the surface of most mammalian cells, function as sensory organelles that monitor extracellular signals and transduce them into intracellular biochemical responses. There is renewed research inte
Autor:
Jin Hong Kim, Abdo J. Najy, Jian Li, Xu Luo, Hyeong‐Reh C. Kim, Mohammad Haroon Asif Choudry, Yong J. Lee
Publikováno v:
Journal of Cellular Physiology. 237:4180-4196
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor-mediated extrinsic apoptosis, specifically in cancer cells, and Bid (BH3-interacting domain death agonist) plays an important role in TRAIL-induced apoptosis. Ferr
Autor:
Nasim Ebrahimi, Jamileh Saremi, Masoud Ghanaatian, Elnaz Yazdani, Samaneh Adelian, Sahar Samsami, Neda Moradi, Nadi Rostami Ravari, Amirhossein Ahmadi, Michael R. Hamblin, Amir Reza Aref
Publikováno v:
Journal of Cellular Physiology. 237:3752-3767
Cancer cells must overcome a variety of external and internal stresses to survive and proliferate. These unfavorable conditions include the accumulation of mutations, nutrient deficiency, oxidative stress, and hypoxia. These stresses can cause aggreg
Autor:
Sevilay Goktas Sahoglu, Yusuf Enes Kazci, Erkan Tuncay, Tugce Torun, Celal Akdeniz, Volkan Tuzcu, Esra Cagavi
Publikováno v:
Journal of Cellular Physiology. 237:3900-3911
Tachycardia is characterized by high beating rates that can lead to life-threatening fibrillations. Mutations in several ion-channel genes were implicated with tachycardia; however, the complex genetic contributors and their modes of action are still
Autor:
Habib Yaribeygi, Mina Maleki, Fatemeh Nasimi, Alexandra E. Butler, Tannaz Jamialahmadi, Amirhossein Sahebkar
Publikováno v:
Journal of Cellular Physiology. 237:3778-3787
Many patients with diabetes mellitus, especially those with chronic kidney disorders, have some degree of anemia due to a spectrum of causes and underlying pathophysiologic pathways. As such, enhancement in erythropoiesis is important in these patien
Publikováno v:
Journal of Cellular Physiology. 237:3872-3882
A variety of biophysical properties are known to regulate angiogenic sprouting, and in vitro systems can parse the individual effects of these factors in a controlled setting. Here, a three-dimensional brain microvascular model interrogates how varia
Autor:
Shau‐Hsuan Li, Limei Qian, Yen‐Hao Chen, Hung‐I Lu, Hsin‐Ting Tsai, Haiwen Lyu, Runxiang Yang, Chang‐Han Chen
Publikováno v:
Journal of Cellular Physiology. 237:3671-3686
Myosin-related proteins play an important role in cancer progression. However, the clinical significance, biological functions, and mechanisms of myosin 1B (MYO1B), in esophageal squamous cell carcinoma (ESCC) remain unclear. The clinical relevance o