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Autor:
Junmin Hong, Kang Xu, Christopher K. Kepler, Weijian Chen, Jiansen Yan, Dongsheng Huang, Shuangxing Li, Anjing Liang, Yingjie Huang, Dessislava Markova, Wei Ye, Jie Zhou
Publikováno v:
Journal of Cellular Physiology. 235:5736-5749
An imbalance between matrix synthesis and degradation is the hallmark of intervertebral disc degeneration while inflammatory cytokines contribute to the imbalance. Bromodomain and extra-terminal domain (BET) family is associated with the pathogenesis
Publikováno v:
Journal of Cellular Physiology. 235:8199-8209
Hepatocellular carcinoma (HCC) is one of the malignant cancers with high incidence and mortality rates worldwide. RNA-binding protein eukaryotic initiation Factor 4A-III (eIF4AIII) is a carcinogene in the biological process of tumors and microRNA (mi
Publikováno v:
Journal of Cellular Physiology. 235:5711-5721
Dysregulation of microRNAs (miRNAs) expression has been demonstrated in gastrointestinal stromal tumor (GIST). In this study, we aimed to determine the differential miRNAs expression in GISTs and explore the functional mechanism of differential miRNA
Autor:
Alessandro Sgambato, Alma Boninsegna, Filomena Colella, Donatella Lucchetti, Claudio Ricciardi-Tenore, Luigi Perelli, Ruggero De Maria, Gian Luca Scoarughi, Gaetano Barbato
Publikováno v:
Journal of Cellular Physiology. 235:5363-5377
Ultrasound (US) offers potentially important opportunities from a therapeutic point of view. Thus, the study of the biological effects of US on cancer cells is important to understand the consequences of these changes on the malignant phenotype. This
Autor:
Hadi Bakhtiari, Hossein Khanahmad, Negar Dinarvand, Abdolkarim Sheikhi, Morteza Pourfarzam, Bahman Rashidi, Sayyed Mohammad Reza Hakimian
Publikováno v:
Journal of Cellular Physiology. 235:5835-5846
Breast cancer (BC) is an important cause of female cancer-related death. It has recently been demonstrated that metabolic disorders including lipid metabolism are a hallmark of cancer cells. Lipin-1 is an enzyme that displays phosphatidate phosphatas
Publikováno v:
Journal of Cellular Physiology. 235:6536-6547
Acute myeloid leukemia (AML) is a highly aggressive disease that causes high mortality. Long noncoding RNA (lncRNA) have studied in recent years that could be a potential biomarker and therapeutic target. Therefore, it is urgently necessary to explor
Publikováno v:
Journal of Cellular Physiology. 235:8224-8235
Esophageal squamous cell carcinoma (ESCC) is the predominant esophageal cancer type in China. The aberrant activation of glioma-associated oncogene homolog1 (Gli1), a key factor in Hedgehog (Hh) signaling pathway, has been found in esophageal carcino
Autor:
Md. Saimul Islam, Susanta Roychoudhury, Mukta Basu, Chinmay Kumar Panda, Neyaz Alam, Anup Roy, Hemantika Dasgupta
Publikováno v:
Journal of Cellular Physiology. 235:8114-8128
Triple negative breast cancer (TNBC) originates from a less differentiated ductal cell of breast, which is less sensitive to chemotherapy. The chemotolerance mechanism of TNBC has not yet been studied in detail. For this reason, molecular profiles (e
Publikováno v:
Journal of Cellular Physiology. 235:7923-7932
Increasing evidence indicates that long noncoding RNAs (lncRNAs) play pivotal roles during tumorigenesis in multiple types of cancers. However, little is known about the exact role of plasmacytoma variant translocation 1 (PVT1) in human pan-cancer. H
Autor:
Ainaz Mihanfar, Mehdi Yousefi, Maryam Abolghasemi, Mahdi Edalati, Hossein Samadi Kafil, Vahid Rameshknia, Niloufar Targhazeh, Ansar Karimian, Ata Mahmoodpoor, Milad Bastami, Bahman Yousefi, Sadra Samavarchi Tehrani, Amin Safa, Aliakbar Ghamari, Tooba Yousefi, Mohsen Naghizadeh, Farhad Jadidi-Niaragh, Maryam Majidinia, Shirin Eyvazi
Publikováno v:
Journal of Cellular Physiology. 235:5059-5071
Breast cancer is a major clinical challenge that affects a wide range of the female population and heavily burdens the health system. In the past few decades, attempts have been made to understand the etiology of breast cancer, possible environmental