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Publikováno v:
Journal of Cellular Physiology. 237:523-531
Hsa-miR-599 was identified as a tumor suppressor against cancer. This study aimed to explore possible mechanisms of antitumor effect of hsa-miR-599 against breast cancer. Tissue specimens were collected from 106 breast cancer cases, and breast cancer
Publikováno v:
Journal of Cellular Physiology. 236:7071-7087
Programmed death ligand 1 (PD-L1) plays a significant role in colorectal tumorigenesis through induction of regulatory T cells (Tregs) and suppression of antitumor immunity. Furthermore, microRNAs (miRNAs) as the posttranscriptional regulators of gen
Publikováno v:
Journal of Cellular Physiology. 236:5620-5632
Lung adenocarcinoma (LUAD) is the most important histological type of lung cancer. We aimed to identify the role of long noncoding RNA family with sequence similarity 201-member A (FAM201A) in the occurrence and development of LUAD. The expressions o
Autor:
Katterine Salazar, Iván González-Chavarría, Francisco Nualart, Eder Ramírez, Nery Jara, Francisca Espinoza, Luciano Ferrada
Publikováno v:
Journal of Cellular Physiology. 236:5801-5817
Glioblastoma multiforme (GBM) is the most common and aggressive brain tumor with a median survival of 14.6 months. GBM is highly resistant to radio- and chemotherapy, and remains without a cure; hence, new treatment strategies are constantly sought.
Autor:
Arunachalam Chinnathambi, Young Yun Jung, Jae-Young Um, Jeong-Hyeon Ko, Sulaiman Ali Alharbi, Kwang Seok Ahn, Gautam Sethi
Publikováno v:
Journal of Cellular Physiology. 236:5253-5264
Hypercholesterolemia has been found to be closely linked with a significant increase in both cancer incidence and mortality. However, the exact correlation between serum cholesterol levels and cancer has not been completely deciphered. Here we analyz
Autor:
Joakim Håkansson, Anna Gustafsson, Elena Garre, Anders Ståhlberg, Göran Landberg, Maria Carmen Leiva, Yalda Bogestål, Andreas Svanström
Publikováno v:
Journal of Cellular Physiology
Breast cancer is a heterogeneous disease where the tumor microenvironment, including extracellular components, plays a crucial role in tumor progression, potentially modulating treatment response. Different approaches have been used to develop three
Autor:
Chang-Chang Jia, Meihai Deng, Zhicheng Yao, Xiu-Rong Cai, Qi Zhang, Li-Yun Zhao, Ze-Xiao Lin, Shaohong Chen
Publikováno v:
Journal of Cellular Physiology. 236:1252-1269
Circular RNAs (circRNA) have been reported as regulators involved in hepatocellular carcinoma (HCC), but their mechanism of activity remains unknown. This study performed quantitative reverse-transcription polymerase chain reaction to determine if ci
Publikováno v:
Journal of Cellular Physiology. 236:612-624
Hsa_circ_001988 has been identified as a tumor suppressor gene in several carcinomas. However, its expression pattern and role in gastric cancer (GC) have still remained elusive. This study aimed to explore the functions of hsa_circ_001988 in GC. Qua
Autor:
Yuyan Xiong, Kayluz Frias Boligan, Diogo Ladeiras, Yi Yu, Stephan von Gunten, Xiu-Fen Ming, Zhihong Yang, Robert E. Hunger, Xiujie Liang
Publikováno v:
Journal of Cellular Physiology. 235:9997-10011
Elevated arginase type II (Arg-II) associates with higher grade tumors. Its function and underlying molecular mechanisms in melanoma remain elusive. In the present study, we observed a significantly higher frequency of Arg-II expression in melanoma o
Autor:
Farhad Jadidi-Niaragh, Sadaf Moghadaszadeh Ardebili, Narges Rostami, Afshin Nikkhoo, Melika Sadat Haeri, Masoumeh Baghaei, Ghasem Ghalamfarsa, Mehdi Yousefi, Navideh Haghnavaz, Fatemeh Atyabi, Shohreh Farhadi, Yalda Khazaei-Poul, Gholamabas Sabz, Afshin Namdar, Nasimeh Aghaei Vanda, Tohid Kazemi
Publikováno v:
Journal of Cellular Physiology. 235:9702-9717
There is an interconnected network between S1P/sphingosine-1-phosphate receptor 1 (S1PR1), IL-6/glycoprotein 130 (GP130), and signal transducer and activator of transcription 3 (STAT3) signaling pathways in the tumor microenvironment, which leads to