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Autor:
Jianhui Wei, Yongjian Cui, Lei Zheng, Jianhui Mao, Hong Guo, Naiyi Du, Zhaosheng Sun, Zhenmin Hao
Publikováno v:
Journal of Cellular Physiology
The purpose of this study was to investigate the role of Poly (C)‐binding protein 2 (PCBP2) and the related signaling pathway in glioma progression. Quantitative real‐time polymerase chain reaction (qRT‐PCR) and immunohistochemistry (IHC) were
Publikováno v:
Journal of Cellular Physiology
Glioblastoma multiforme (GBM) is a highly proliferative cancer with generally poor prognosis and accumulating evidence has highlighted the potential of long noncoding RNAs (lncRNAs) in the biological behaviors of glioma cells. This study focused on t
Autor:
Qiujing Zhang, Xueli Nan, Jia Wang, Qingqing Zhu, Jie Liu, Chao Xie, Chengxiang Liu, Lihua Fang, Fuxia Wang, Bao Song, Shuai Fu
Publikováno v:
Journal of Cellular Physiology
With the participation of the existing treatment methods, the prognosis of advanced clear‐cell renal cell carcinoma (ccRCC) is poor. More evidence indicates the presence of methylation in ccRCC cancer cells, but there is a lack of studies on methyl
Publikováno v:
Journal of Cellular Physiology
There is growing evidence that alternative splicing (AS) plays an important role in cancer development. However, a comprehensive analysis of AS signatures in kidney renal clear cell carcinoma (KIRC) is lacking and urgently needed. It remains unclear
Autor:
Xirui Liu, Bo Zhang, Yifeng Cui, Jihua Han, Zhaoyang Lu, Lianxin Liu, Fanzheng Meng, Ruipeng Song, Shangha Pan, Hongrui Guo, Yan Wang, Yufeng Liu, Yaliang Lan, Dan Sun, Shugeng Zhang, Shuhang Liang
Publikováno v:
Journal of Cellular Physiology
Cystatin SN, a specific cysteine protease inhibitor, is thought to be involved in various malignant tumors. Therefore, we evaluated the role of cystatin SN in hepatocellular carcinoma (HCC). Notably, cystatin SN was elevated in tumorous samples and c
Autor:
Guoyan Liu, Yuling Hong, Kun Lu, Fan Liu, Xiao-Ling Deng, Li Yin, Haifeng Qin, Song-Lin Shi, Liu Lei, Li Long, Xunrong Zhuang, Yuhai Zhang
Publikováno v:
Journal of Cellular Physiology
Circular RNAs (circRNAs) are a new class of RNAs, and many studies have identified thousands of circRNAs in tumor cells. Fibronectin type III domain‐containing protein 3B (FNDC3B) circular RNA (circFNDC3B, circBase ID: hsa_circ_0006156) circularize
Publikováno v:
Journal of Cellular Physiology
MicroRNAs are beneficial for cancer therapy as they can simultaneously downregulate multiple targets involved in diverse biological pathways related to tumor development. In papillary thyroid cancer, many microRNAs were identified as differentially e
Publikováno v:
Journal of Cellular Physiology
Clear cell renal cell carcinoma (ccRCC) is a common urinary neoplasm, looking for useful candidates to establish scientific foundation for the therapy of ccRCC is urgent. We downloaded genomic profiles of GSE781, GSE6244, GSE53757, and GSE66271 from
Publikováno v:
Journal of Cellular Physiology
We have recently reported that type 2 diabetes promotes centrosome amplification via enhancing the expression, biding, and centrosome translocation of rho‐associated coiled‐coil containing protein kinase 1 (ROCK1)/14‐3‐3σ complex in HCT116 c
Autor:
Taichi Hattori, Teppei Jinno, Seiji Nakamura, Ryota Matsubara, H. Tanaka, Kaori Yasuda, Masahiko Morioka, Yuma Hashiguchi, Naoki Kaneko, Tamotsu Kiyoshima, Yasuyuki Maruse, Shoichi Tanaka, Shintaro Kawano, Taiki Sakamoto, Yuichi Goto
Publikováno v:
Journal of Cellular Physiology
We previously revealed that epithelial-to-mesenchymal transition (EMT) was mediated by ΔNp63β, a splicing variant of ΔNp63, in oral squamous cell carcinoma (OSCC). Recent studies have highlighted the involvement of microRNA (miRNA) in EMT of cance