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Autor:
Alain de Bruin, Louis C. Penning, Marianna A. Tryfonidou, Frances C. Bach, Richard Wubbolts, Kristyanne Hendriks, Ger J Arkesteijn, Frank M. Riemers, Kirsten Rutten, Peter W. A. Cornelissen, William A. Horton
Publikováno v:
Journal of Cellular Physiology
The endocrine feedback loop between vitamin D3(1,25(OH)2D3) and parathyroid hormone (PTH) plays a central role in skeletal development. PTH-related protein (PTHrP) shares homology and its receptor (PTHR1) with PTH. The aim of this study was to invest
Publikováno v:
Journal of Cellular Physiology
The capacity of embryonic stem (ES) cells to differentiate into cell lineages comprising the three germ layers makes them powerful tools for studying mammalian early embryonic development in vitro. The human body consists of approximately 210 differe
Autor:
Shiming Liu, Dong-Cheng Zhang, Min-Sheng Chen, Jiao Li, Zhenhui Zhang, Yun Zhong, Jun Dong, Xiang-Yu You
Publikováno v:
Journal of Cellular Physiology
miRNAs have recently been shown to play a significant role in human aging. However, data demonstrating the effects of aging-related miRNAs in human mesenchymal stem cells (hMSCs) are limited. We observed that hMSC differentiation decreased with aging