Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Yong J. Lee"'
Autor:
Yong J. Lee, Chuanyue Wu, Se Hoon Hong, David L. Bartlett, Seog Young Kim, Yong Tae Kwon, Per H. Basse
Publikováno v:
Journal of Cellular Biochemistry. 117:2289-2301
Cancer stem cells (CSCs) are capable of initiation and metastasis of tumors. Therefore, understanding the biology of CSCs and the interaction between CSCs and their counterpart non-stem cells is crucial for developing a novel cancer therapy. We used
Autor:
Yong J. Lee, Ki Sa Sung, William T. Kwon, Zong Sheng Guo, Dae Hee Lee, David L. Bartlett, Yong Tae Kwon, Sang Cheul Oh
Publikováno v:
Journal of Cellular Biochemistry. 117:1078-1091
It is well known that tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis can be initially triggered by surface death receptors (the extrinsic pathway) and subsequently amplified through mitochondrial dysfunction (the in
Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5
Autor:
Dae Hee Lee, Jian Yu, David L. Bartlett, Yong Seok Park, Haroon A. Choudry, Yong J. Lee, Seong Hye Park, So Yeon Jeong, Young Sun Lee, Sang Cheul Oh
Publikováno v:
Journal of cellular biochemistry. 120(1)
Ferroptosis is considered genetically and biochemically distinct from other forms of cell death. In this study, we examined whether ferroptosis shares cell death pathways with other types of cell death. When human colon cancer HCT116, CX-1, and LS174
Publikováno v:
Journal of Cellular Biochemistry. 112:118-127
The aim of this study was to investigate the effect of garlic constituent diallyl trisulfide (DATS) on the cell-death signaling pathway in a human breast cell line (MDA-MB-231). We observed that DATS (10-100 µM) treatment resulted in dose- and time-
Autor:
Marco A. Alcala, Jinsang Yoo, David L. Bartlett, Byeong-Chel Lee, Bae-Hang Park, Dae Hee Lee, Kyung Soo Park, Yong J. Lee
Publikováno v:
Journal of Cellular Biochemistry. 110:1073-1081
Approximately 25% of patients with colorectal cancer develop metastases to the liver, and surgery is currently the best treatment available. But there are several patients who are unresectable, and isolated hepatic perfusion (IHP) offers a different
Publikováno v:
Journal of Cellular Biochemistry. 105:585-595
Her-2/neu (ErbB2) is a transmembrane tyrosine kinase and acts as a co-receptor for the other EGFR family members. It is well known that high expression of Her-2/neu is associated with a poor prognosis in breast cancer. Quercetin, a flavonoid present
Autor:
Dae Hee Lee, Yong J. Lee
Publikováno v:
Journal of Cellular Biochemistry. 105:546-553
Quercetin, a ubiquitous bioactive plant flavonoid, has been shown to inhibit the proliferation of cancer cells and induce the accumulation of hypoxia-inducible factor-1alpha (HIF-1alpha) in normoxia. In this study, under hypoxic conditions (1% O(2)),
Publikováno v:
Journal of Cellular Biochemistry. 104:1172-1180
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily. TRAIL shows strong cytotoxicity to many cancer cells but minimal cytotoxicity to most normal cells. Interestingly, our recent studies have demonstrate
Publikováno v:
Journal of Cellular Biochemistry. 103:1989-1998
Hypoxia-inducible factor-1 alpha (HIF-1alpha) is the regulatory subunit of the heterodimeric transcription factor HIF-1 that is the key regulator of cellular response to low oxygen tension. Under normoxic conditions, HIF-1alpha is continuously degrad
Autor:
Yong J. Lee, Young-Ho Kim
Publikováno v:
Journal of Cellular Biochemistry. 100:998-1009
TNF-related apoptosis-inducing ligand (TRAIL) is a promising cancer therapy that preferentially induces apoptosis in cancer cells. However, many neoplasms are resistant to TRAIL by mechanisms that are poorly understood. Here we demonstrated that huma