Zobrazeno 1 - 10
of 5 582
pro vyhledávání: ''
Autor:
Ajmal Ahmad, Mohd Imtiaz Nawaz
Publikováno v:
Journal of Cellular Biochemistry. 123:1938-1965
Over the last seven decades, a significant scientific contribution took place in the delineation of the implications of vascular endothelial-derived growth factor (VEGF) in the processes of angiogenesis. Under pathological conditions, mainly in respo
Autor:
Mariana C. S. Mancini, Ana P. Morelli, Matheus B. Severino, Isadora C. B. Pavan, Érika P. Zambalde, Mariana M. Góis, Luiz G. S. da Silva, Nathalia Quintero‐Ruiz, Caio F. Romeiro, Daniel F. G. dos Santos, Rosângela M. N. Bezerra, Fernando M. Simabuco
Publikováno v:
Journal of Cellular Biochemistry. 123:2079-2092
Prostate cancer (PCa) represents the second most common cancer in men and affects millions worldwide. Chemotherapy is a common treatment for PCa but the development of resistance is often a problem during therapy. NRF2 (nuclear factor erythroid 2-rel
Autor:
Mahzeiar Samadaei, Daniel Senfter, Sibylle Madlener, Karolina Uranowska, Christine Hafner, Michael Trauner, Nataliya Rohr‐Udilova, Matthias Pinter
Publikováno v:
Journal of Cellular Biochemistry. 123:1663-1673
The multityrosine kinase inhibitor sorafenib remains an important systemic treatment option for hepatocellular carcinoma (HCC). Signaling pathways, which are targeted by sorafenib, are involved in checkpoint and DNA repair response, RAD51 being a can
Autor:
Hossein Javid, Pedram Hashemian, Shaghayegh Yazdani, Alireza Sharbaf Mashhad, Mehdi Karimi‐Shahri
Publikováno v:
Journal of Cellular Biochemistry. 123:1704-1735
Heat shock proteins (HSPs) are a large molecular chaperone family classified by their molecular weights, including HSP27, HSP40, HSP60, HSP70, HSP90, and HSP110. HSPs are likely to have antiapoptotic properties and participate actively in various pro
Autor:
Liuying Chen, Huiqian Fan, Huikuan Chu, Fan Du, Yixiong Chen, Lilin Hu, Zhonglin Li, Weijun Wang, Xiaohua Hou, Ling Yang
Publikováno v:
Journal of Cellular Biochemistry. 123:1857-1872
Cholangiocyte death accompanied by the progression of primary biliary cholangitis (PBC) has not yet been thoroughly investigated. Thus, we are aimed to explore the role of HSP90 and a potential treatment strategy in cholangiocyte necroptosis. First,
Autor:
Kriti Sharma, Pallavi Awasthi, Ravi Prakash, Sonu Khanka, Ranju Bajpai, Amogh A. Sahasrabuddhe, Atul Goel, Divya Singh
Publikováno v:
Journal of Cellular Biochemistry. 123:1762-1779
Osteoporosis is a metabolic bone disorder associated with impaired bone microarchitecture leading to fragility fractures. Long-term usage of parathyroid hormone (PTH) enhances bone resorption and leads to osteosarcoma in rats which limits its exposur
Publikováno v:
Journal of Cellular Biochemistry. 123:1817-1826
Understanding the mechanisms responsible for the kidney's defense against ascending uropathogen is critical to devise novel treatment strategies against increasingly antibiotic resistant uropathogen. Growing body of evidence indicate Intercalated cel
Autor:
Rayne S. S. Magalhães, Fernanda C. Boechat, Aline A. Brasil, José. R. M. Neto, Gabriela D. Ribeiro, Luan H. Paranhos, Natália Neves de Souza, Tuane Vieira, Tiago F. Outeiro, Bianca C. Neves, Elis C. A. Eleutherio
Publikováno v:
Journal of cellular biochemistry 123(11), 1808-1816 (2022). doi:10.1002/jcb.30317
Cancer-related metabolic features are in part maintained by hexokinase 2 upregulation, which leads to high levels of glucose-6-phosphate (G6P) and is needed to provide energy and biomass to support rapid proliferation. Using a humanized model of the
Autor:
Shirin Saberianpour, Samaneh Abolbashari, Mohamad H. S. Modaghegh, Maryam S. Karimian, Ali H. Eid, Thozhukat Sathyapalan, Amirhossein Sahebkar
Publikováno v:
Journal of Cellular Biochemistry. 123:1285-1297
Osteoarthritis (OA) is a progressive joint disease. The etiology of OA is considered to be multifactorial. Currently, there is no definitive treatment for OA, and the existing treatments are not very effective. Hypercholesterolemia is considered a no
Publikováno v:
Journal of Cellular Biochemistry. 123:1467-1480
The mutations at the hotspot region of K-Ras result in the progression of cancer types. Our study aimed to explore the small molecule inhibitors against the G13D mutant K-Ras model with anti-cancerous activity from food and drug administration (FDA)-