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Publikováno v:
Journal of Cellular Biochemistry. 122:1686-1700
Mitochondria and peroxisomes are metabolically interconnected and functionally active subcellular organelles. These two dynamic organelles, share a number of common biochemical functions such as β-oxidation of fatty acids and detoxification of perox
Publikováno v:
Journal of Cellular Biochemistry
WNT5A activates noncanonical Wnt signaling pathways and has critical functions in early development, differentiation, and tissue homeostasis. Two major WNT5A protein isoforms, which in this study we term WNT5A‐L(A) and WNT5A‐S(B), have been ident
Publikováno v:
Journal of Cellular Biochemistry. 121:3266-3277
Bone morphogenetic proteins regulate a diverse range of biological processes through their activation of SMAD1, SMAD5, or SMAD8 proteins that, in turn, regulate gene expression. These SMAD transcription factors achieve a layer of functional specifici
Publikováno v:
Journal of Cellular Biochemistry. 121:2385-2393
Background Breast cancer (BC) is a common malignant tumor and its incidence and mortality rates are ranked first among female cancers. So far, there has been no effective biomarkers for BC prognosis. Methods The DNA methylation data of BC was downloa
Autor:
Chen Yu, Fengchun Zhang
Publikováno v:
Journal of Cellular Biochemistry. 121:1934-1944
PURPOSE Long noncoding RNAs (lncRNAs) play an indispensable role in cancer progression. We aim at exploring the effect of AC009022.1 on colorectal cancer (CRC) development in this paper. METHODS CRC tissues and matched normal tissues of 68 CRC patien
Autor:
Mohammad Hossein Ghahremani, Jafar Kiani, Zahra Jabbarpour, Naser Ahmadbeigi, Massoud Saidijam, Somayeh Keshtkar
Publikováno v:
Journal of Cellular Biochemistry. 121:1362-1373
Poor prognosis and low survival are commonly seen in patients with glioblastoma multiforme (GBM). Due to the specific nature of solid tumors such as GBM, delivery of therapeutic agents to the tumor sites is difficult. So, one of the major challenges
Publikováno v:
Journal of Cellular Biochemistry. 121:1227-1237
Background Toll-like receptor-7 (TLR7) is functionally involved in the pathogenesis of Hunner-type interstitial cystitis (HIC). In addition, maternally expressed gene 3 (MEG3) is implicated in many urethral diseases. In this study, we aimed to verify
Autor:
Kim H. R. Mulders, Jehad Z. Tayyeb, Ronald P. Mensink, Herman E. Popeijus, Jogchum Plat, Maurice C. J. M. Konings
Publikováno v:
Journal of Cellular Biochemistry, 120(10), 17219-17227. Wiley
Journal of Cellular Biochemistry
Journal of Cellular Biochemistry
Background Apolipoprotein-I (ApoA-I), the major component of high-density lipoprotein (HDL) particles, mediates cholesterol efflux by which it facilitates the removal of excess cholesterol from peripheral tissues. Therefore, elevating ApoA-I producti
Publikováno v:
Journal of Cellular Biochemistry. 121:1563-1574
Background Acute myeloid leukemia (AML) with -5/del(5q) or -7/del(7q) has special clinical and biological characteristics, but its molecular mechanisms and risk stratification remain unknown. Methods The RNA sequencing and DNA methylation of 23 patie
Publikováno v:
Journal of Cellular Biochemistry. 120:19310-19317
Purpose The aim of this study was to determine the biological function of pyridine nucleotide-disulfide oxidoreductase domain 1 (PYROXD1), a recently discovered protein, in colon cancer cell line HCT116. Methods The small interfering RNA (siRNA) was