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Autor:
Samkeliso Dlamini, William R. Taylor, Viranga Tillekeratne, Jade McDaniel, Nishanth Kuganesan
Publikováno v:
J Cell Biochem
Ferroptosis is a form of iron-dependent cell death characterized by elevated lipid peroxides and reactive oxygen species (ROS). Glutathione (GSH) plays an essential role in scavenging ROS to maintain cell viability and acts as a cofactor of GSH perox
Autor:
Elżbieta Karnas, Elżbieta Boratyn, Dawid Wnuk, Małgorzata Durbas, Hanna Rokita, Anna Polus, Damian Ryszawy, Iwona Nowak, Irena Horwacik
Publikováno v:
Journal of Cellular Biochemistry. 121:3406-3425
Monocyte chemoattractant protein-1-induced protein 1 (MCPIP1) has a multidomain structure, which assures its pleiotropic activity. The physiological functions of this protein include repression of inflammatory processes and the prevention of immune d
Publikováno v:
Journal of Cellular Biochemistry. 121:4120-4129
Infection of human papillomaviruses (HPVs), such as subtypes HPV16 and HPV18 is carcinogenic to human and is prominent cause of HPV-positive cervical carcinoma (CC). A closer investigation into the mechanism of HPV-induced CC may stimulate the genera
Publikováno v:
Journal of Cellular Biochemistry. 121:4064-4073
Osteosarcoma (OS) is the most frequent type of cancer that starts in the bones, with a rather high tendency to metastasize to other bones at the early stages. Although many types of research have demonstrated that long noncoding RNAs commonly take pa
Publikováno v:
Journal of Cellular Biochemistry. 121:3584-3592
Cisplatin is one of the conventional drugs used in chemotherapy which has a potent antitumor function. However, due to the dangerous side effects, including the damage to DNA of the normal cells, its clinical use is limited. The aim of this study was
Publikováno v:
Journal of Cellular Biochemistry. 121:3010-3023
Adipose tissue is an important source of adipokines involved in anti- and pro-inflammatory effects. Their involvement in certain cancers such as breast and colon cancer is known but in gliomas it remains unexplored till date. The aim of this study wa
Autor:
Jane E. Cavanaugh, Darlene Monlish, Suravi Chakrabarty, Christopher Raybuck, Mohit Gupta, Katy Wendekier, Akshita B. Bhatt, Nathan Gartland, Patrick T. Flaherty, Thomas D. Wright, Matthew E. Burow
Publikováno v:
J Cell Biochem
Triple-negative breast cancers (TNBCs) represent 15% to 20% of all breast cancers and are often associated with poor prognosis. The lack of targeted therapies for TNBCs contributes to higher mortality rates. Aberrations in the phosphoinositide-3-kina
Publikováno v:
J Cell Biochem
Pancreatic tumors are highly desmoplastic and poorly-vascularized, and therefore must develop adaptive mechanisms to sustain their survival under hypoxic condition. Extracellular vesicles (EV) play vital roles in pancreatic tumor pathobiology by faci
Autor:
Gianluca Sala, Beatrice Dufrusine, Margot De Marco, Emily Capone, Liberato Marzullo, Michele Sallese, Enrico Dainese, Maria Caterina Turco, Francesca Reppucci, Damiana Pieragostino, Verena Damiani, Alessandra Rosati, Vincenzo De Laurenzi
Publikováno v:
Journal of cellular biochemistry. 123(1)
Pancreatic ductal adenoma carcinoma (PDAC) is considered one of the deadliest solid cancers as it is usually diagnosed in advanced stages and has a poor response to treatment. The enormous effort made in the last 2 decades in the oncology field has n
Publikováno v:
Journal of Cellular Biochemistry. 120:18650-18658
This study aims to explore the ability of magnetic resonance imaging (MRI) in mucin 1 (MUC1) modified superparamagnetic iron oxide nanoparticle (SPION) targeting human pancreatic cancer (PC). The MUC1 target-directed probe was prepared through MUC1 c