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Publikováno v:
Journal of Cellular Biochemistry. 121:4226-4238
Lung adenocarcinoma (LUAD), a general kind of bronchogenic malignancy globally, is depicted as one of the most critical factors affecting human health severely. Featured with loop structure, circular RNA (circRNA) has been described as an essential r
Publikováno v:
Journal of Cellular Biochemistry. 121:4064-4073
Osteosarcoma (OS) is the most frequent type of cancer that starts in the bones, with a rather high tendency to metastasize to other bones at the early stages. Although many types of research have demonstrated that long noncoding RNAs commonly take pa
Publikováno v:
Journal of Cellular Biochemistry. 121:4085-4093
Kidney renal clear cell carcinoma (KIRC) is the most general subtype of renal cell carcinoma, which composes about 1/20 of adult malignancies. The anomaly of long noncoding RNAs (lncRNAs) expression is proved to mediate cancer progression of various
Publikováno v:
Journal of Cellular Biochemistry. 121:4214-4225
The study aimed to investigate the expression and function of bladder cancer (BC) long noncoding RNAs (lncRNAs) using a high-throughput platform. High-throughput sequencing was used to compare the expression profiles of lncRNA in BC and adjacent norm
Autor:
Chen Yu, Fengchun Zhang
Publikováno v:
Journal of Cellular Biochemistry. 121:1934-1944
PURPOSE Long noncoding RNAs (lncRNAs) play an indispensable role in cancer progression. We aim at exploring the effect of AC009022.1 on colorectal cancer (CRC) development in this paper. METHODS CRC tissues and matched normal tissues of 68 CRC patien
Publikováno v:
Journal of Cellular Biochemistry. 121:1216-1226
MicroRNAs (miRs) are short noncoding RNAs that play key regulatory roles in osteoblast differentiation. In this study, the specific regulatory roles of miR-218-5p on postmenopausal osteoporosis (PMOP) were investigated. The mouse model of PMOP was es
Autor:
Yingmin Kuang, Zhao Lei, Yang Yuye, Qiao Zhang, Yang Lijuan, Yueli Ni, Yuechun Zhu, Jiang Lu, Huixin Yang, Zihan Yi, Mingjia Deng, Zhou Meiling
Publikováno v:
Journal of Cellular Biochemistry. 120:19124-19136
In this study, we aimed to explore the mechanism of glutathione peroxidase 3 (GPX3) in the growth of malignant melanoma (MM) cells by hypoxia-inducible factor-1α (HIF1-α) and HIF2-α regulating the metabolism through reactive oxygen species (ROS).
Publikováno v:
Journal of Cellular Biochemistry. 121:322-331
Retinoblastoma (RB) is the most common intraocular malignancy in infants and children. S-phase kinase-associated protein 2 (SKP2) has been unmasked as an oncogene in a great many of carcinomas. The biologic function and the detailed molecular mechani
Publikováno v:
Journal of Cellular Biochemistry. 120:13985-13993
Matrix attachment regions (MARs) can enhance transgene expression levels and maintain stability. However, the consensus sequence from MARs and its functional analysis remains to be examined. Here, we assessed a possible consensus sequence from MARs a
Publikováno v:
Journal of Cellular Biochemistry. 120:12724-12739
The quail oviduct (Coturnix c. japonica) is a natural candidate avian bioreactor, while the secretive quail oviduct epithelial cells (QOECs) are potential in vitro producers of recombinant proteins and vaccines. In view of the need for highly perform