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BAG3 is a negative regulator of ciliogenesis in glioblastoma and triple‐negative breast cancer cells
Publikováno v:
Journal of Cellular Biochemistry. 123:77-90
By regulating several hallmarks of cancer, BAG3 exerts oncogenic functions in a wide variety of malignant diseases including glioblastoma (GBM) and triple-negative breast cancer (TNBC). Here we performed global proteomic/phosphoproteomic analyses of
Autor:
Van T. Hoang, Jacqueline La, Brian G. Rowan, Saloni Patel, Aaron Buechlein, Matthew E. Burow, Bridgette M. Collins-Burow, Margarite D. Matossian, Lucio Miele, Douglas B. Rusch, Akshita B. Bhatt, Murali Anbalagan, Douglas B. Chrisey, Thomas D. Wright, Jane E. Cavanaugh, Kristine Hoang, Steven Elliott, Patrick T. Flaherty, Kenneth P. Nephew, Deniz A. Ucar, Theresa B. Phamduy, Hope E. Burks
Publikováno v:
Journal of Cellular Biochemistry. 122:835-850
Triple-negative breast cancer (TNBC) presents a clinical challenge due to the aggressive nature of the disease and a lack of targeted therapies. Constitutive activation of the mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kin
Publikováno v:
Journal of Cellular Biochemistry. 122:394-402
Epidermal growth factor receptor (EGFR) induces peroxisome-proliferator-activated receptor-δ (PPARδ)-Y108 phosphorylation, while it is unclear the effect of phosphorylation of PPARδ on cancer cell metabolism. Here we found that EGF treatment incre
Autor:
Hui Li, Li Hanhan, Tong-Cun Zhang, Jia-Peng Li, Feng Huang, Xing-Hua Liao, Zhang Huimin, Liu Meijun, Zhou-Tong Dai, Chao Jiang Gu, Yuan Xiang
Publikováno v:
Journal of Cellular Biochemistry. 121:3392-3405
Although many methods and new therapeutic drugs have been developed, the overall survival rate and long-term survival rate of patients with gastric cancer (GC) are still not satisfactory. In this study, we investigated the effects of microRNA miR-133
Publikováno v:
Journal of Cellular Biochemistry. 121:3235-3247
Long noncoding RNA HOX antisense intergenic RNA (HOTAIR) is overexpressed in many types of cancers, and substantial evidence has suggested a link between cancers and HOTAIR. In the present study, we reviewed the structure and the corresponding biolog
Publikováno v:
Journal of Cellular Biochemistry. 121:4601-4611
Recently, long noncoding RNAs (lncRNAs) have been reported as a new kind of controllers about cancer processes in biology. In spite of the dysregulation of lncRNAs in various kinds of cancers, only a little of the information was effective on the exp
Publikováno v:
Journal of Cellular Biochemistry. 121:4590-4600
The connection between circular RNAs (circRNAs) and gastric cancer has been reported widely in recent years. However, previous studies have focused mainly on circRNAs from gastric cancer tissue. The objectives of the present study were to detect dysr
Publikováno v:
Journal of Cellular Biochemistry. 121:4064-4073
Osteosarcoma (OS) is the most frequent type of cancer that starts in the bones, with a rather high tendency to metastasize to other bones at the early stages. Although many types of research have demonstrated that long noncoding RNAs commonly take pa
Publikováno v:
Journal of Cellular Biochemistry. 121:4085-4093
Kidney renal clear cell carcinoma (KIRC) is the most general subtype of renal cell carcinoma, which composes about 1/20 of adult malignancies. The anomaly of long noncoding RNAs (lncRNAs) expression is proved to mediate cancer progression of various
Autor:
Xin Zhao, Fangfang Dai, Yuping Liu, Li Zhang, Yanxiang Cheng, Shu Xian, Omer Kamal Mahgoub, Mengqin Yuan, Chenliang Zhou, Yumeng Jin, Feiyan Wang, Shiyi Liu, Saijiao Li, Zihang Zeng, Yanqing Wang, Dongyong Yang
Publikováno v:
Journal of Cellular Biochemistry. 121:2571-2581
In this study, we attempted to evaluate the prognostic value of infiltrating immune/stromal cells in clear cell renal cell carcinoma (ccRCC), by using the immune scores and stromal scores based on the "Estimation of STromal and Immune cells in MAlign