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Autor:
Ann B. Moser, Nancy Braverman, Yanqiu Liu, Ali Fatemi, Shandi Hiebler, Ulrike Schrifl, Paul A. Watkins, Xiaohai Shi, Steven J. Steinberg
Publikováno v:
J Cell Biochem
X-linked adrenoleukodystrophy (XALD) is a genetic neurologic disorder with multiple phenotypic presentations and limited therapeutic options. The childhood cerebral phenotype (CCALD), a fatal demyelinating disorder affecting about 35% of patients, an
Autor:
Jogendra S. Pawar, Archana Varadaraj, Carina Magdaleno, Sophia Carvalho, Narendiran Rajasekaran, Trenton House
Publikováno v:
Journal of Cellular Biochemistry
Fibronectin (FN) is an extracellular matrix (ECM) glycoprotein that self‐assembles into FN fibrils, forming a FN matrix contributing to the stiffness of the ECM. Stromal FN stiffness in cancer has been shown to impact epithelial functions such as m
Publikováno v:
Journal of Cellular Biochemistry. 121:4214-4225
The study aimed to investigate the expression and function of bladder cancer (BC) long noncoding RNAs (lncRNAs) using a high-throughput platform. High-throughput sequencing was used to compare the expression profiles of lncRNA in BC and adjacent norm
Publikováno v:
Journal of Cellular Biochemistry. 121:1911-1922
In spite of the achievement in treatment, the gastric cancer (GC) mortality still remains high. MicroRNAs (miRNAs) are a group of small noncoding RNAs that play a crucial part in tumor progression. In this study, we explored the expression and functi
Autor:
Masood Darabi, Sepideh Maralbashi, Mahsa Javadian, Behzad Baradaran, Mohammad S Soltani-Zangbar, Ali Mohammadi, Dariush Shanehbandi, Najibeh Shekari, Behzad Mansoori, Tohid Kazemi
Publikováno v:
Journal of Cellular Biochemistry. 121:2416-2427
There is insufficient evidence with respect to the effect of the standard anticancer therapeutic agents as well as common dietary supplements on the expression of such genes and microRNAs (miRNAs). Therefore, this study was aimed to study the effect
Publikováno v:
Journal of Cellular Biochemistry. 121:2818-2827
The purpose of this study was to investigate miR-7 overexpression effects on neural differentiation of mesenchymal stem cells (MSCs) on both two-dimensional (2D) and three-dimensional (3D) culture systems. We upregulated miR-7 through lentiviral vect
Publikováno v:
Journal of Cellular Biochemistry. 121:1880-1889
Meningioma, as a sort of the malignantly intracranial tumors, has captured public attention for its second-highest morbidity all over the world. Long noncoding RNAs (lncRNAs), including lncRNA SNHG1, have been well known as essential players in the d
Autor:
Qi Guan, Xing Chang, Minghuan Gao, Zengqiang Li, Di Wu, Binyue Lang, Zi Liu, Weige Zhang, Qile Xu, Daiying Zuo, Yingliang Wu
Publikováno v:
Journal of Cellular Biochemistry. 121:2184-2196
Gastric cancer and cervical cancer are two major malignant tumors that threaten human health. The novel chemotherapeutic drugs are needed urgently to treat gastric cancer and cervical cancer with high anticancer activity and metabolic stability. Prev
Autor:
Bijun Fan, Yu Zheng, Liyan Zhang, Tiancheng Zhang, Yong-Qi Cui, Yueyan Lou, Ke Wang, Xiaoming Tan
Publikováno v:
Journal of Cellular Biochemistry. 121:963-973
Synaptotagmins are a class of proteins that play an important role in the secretion of neurotransmitters by synaptic vesicles. However, recent studies have shown that members of this family also have a certain function in the development of tumors. I
Autor:
Mohammad Hossein Ghahremani, Jafar Kiani, Zahra Jabbarpour, Naser Ahmadbeigi, Massoud Saidijam, Somayeh Keshtkar
Publikováno v:
Journal of Cellular Biochemistry. 121:1362-1373
Poor prognosis and low survival are commonly seen in patients with glioblastoma multiforme (GBM). Due to the specific nature of solid tumors such as GBM, delivery of therapeutic agents to the tumor sites is difficult. So, one of the major challenges