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Autor:
Emanuella Maria Barreto Fonseca, Karin J P Rocha-Brito, Allesandra de Sousa Faria, Igor H. Sampaio, Leonardo R. Silveira, Karla de Souza Queiroz, Renato Milani, Maikel P. Peppelenbosch, Carmen Veríssima Ferreira-Halder, Thais F. Tornatore, Tamira O. Santos
Publikováno v:
Journal of Cellular Biochemistry, 118(11), 3846-3854. Wiley-Liss Inc.
In chemoresistant leukemia cells (Lucena-1), the low molecular weight protein tyrosine phosphatase (LMWPTP) is about 20-fold more active than in their susceptible counterpart (K562). We found this phosphatase ensures the activated statuses of Src and
Autor:
Justus H.W. Jansen, Irene Westbroek, Huib A.P. Pols, J.P.T.M. van Leeuwen, F.A.A. Weyts, Holger Jahr, Harrie Weinans, Jan A N Verhaar, Hideki Chiba
Publikováno v:
Journal of Cellular Biochemistry, 93, 542-551. Wiley-Liss Inc.
The goal of this study was to investigate the effect of mechanical loading on osteoblasts and extracellular signal-regulated kinase (ERK1/2) signaling in relation to osteoblast differentiation and mineralization. A human osteoblast cell line (SV-HFO)
Publikováno v:
Journal of Cellular Biochemistry, 87, 85-92. Wiley-Liss Inc.
Osteoblast growth and differentiation are critical processes for bone development and maintenance, and are regulated by both humoral and mechanical factors. Humoral (hormonal) factors can affect gene transcription via MAPkinases, e.g., extracellular
Publikováno v:
Journal of Cellular Biochemistry, 57, 465-478. Wiley-Liss Inc.
Steroid receptors have been reported to bind to the nuclear matrix. The nuclear matrix is operationally defined as the residual nuclear structure that remains after extraction of most of the chromatin and all soluble and loosely bound components. To