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Autor:
Emanuella Maria Barreto Fonseca, Karin J P Rocha-Brito, Allesandra de Sousa Faria, Igor H. Sampaio, Leonardo R. Silveira, Karla de Souza Queiroz, Renato Milani, Maikel P. Peppelenbosch, Carmen Veríssima Ferreira-Halder, Thais F. Tornatore, Tamira O. Santos
Publikováno v:
Journal of Cellular Biochemistry, 118(11), 3846-3854. Wiley-Liss Inc.
In chemoresistant leukemia cells (Lucena-1), the low molecular weight protein tyrosine phosphatase (LMWPTP) is about 20-fold more active than in their susceptible counterpart (K562). We found this phosphatase ensures the activated statuses of Src and