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Autor:
François Lifermann, Jean-Alain Martignoles, Anne Quinquenel, Vincent Parinet, Christine Lefebvre, Pierre Hirsch, Mélanie Martin, Sabine Defasque, Florence Nguyen-Khac, Matthieu Decamp, Laurence Simon, Dominique Penther, Nadia Ali-Ammar, Elise Chapiro, Odile Maarek, Chrystele Bilhou-Nabera, Baptiste Gaillard, Agathe Maillon, Jean-Baptiste Micol, Marine Baron, Nathalie Auger, Stéphanie Struski, Damien Roos-Weil, Sylvie Tondeur, Marie-Joelle Mozziconacci, Audrey Bidet
Publikováno v:
Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine, Wiley Open Access, 2021, ⟨10.1111/jcmm.16895⟩
Journal of Cellular and Molecular Medicine, 2021, ⟨10.1111/jcmm.16895⟩
Journal of Cellular and Molecular Medicine, Wiley Open Access, 2021, ⟨10.1111/jcmm.16895⟩
Journal of Cellular and Molecular Medicine, 2021, ⟨10.1111/jcmm.16895⟩
International audience; Translocation t(4;12)(q11-13;p13) is a recurrent but very rare chromosomal aberration in acute myeloid leukaemia (AML) resulting in the non-constant expression of a CHIC2/ETV6 fusion transcript. We report clinico-biological fe
Autor:
Melissa Thomas, Izabela Koryga, Adrienne M. Gorman, Leif A. Eriksson, Afshin Samali, Katarzyna Mnich, Karolina Pakos-Zebrucka, Susan E. Logue
Publikováno v:
Journal of Cellular and Molecular Medicine
Stress‐induced apoptosis is mediated primarily through the intrinsic pathway that involves caspase‐9. We previously reported that in caspase‐9‐deficient cells, a protein complex containing ATG5 and Fas‐associated death domain (FADD) facilit
Autor:
Masakatsu Hishizawa, Seishi Ogawa, Toshio Kitawaki, Yasuhito Nannya, Takuya Shimizu, Takero Shindo, Mizuki Watanabe, Kouhei Yamashita, Akifumi Takaori-Kondo, Tadakazu Kondo
Publikováno v:
Journal of Cellular and Molecular Medicine
Acute basophilic leukaemia (ABL) is a rare subtype of acute myeloid leukaemia (AML); therefore, few data are available about its biology. Herein, we analysed two ABL patients using flow cytometry and next-generation sequencing (NGS). Two cell populat
Autor:
Shuiliang Ruan, Wenyan Li, Qiaobing Guan, Yi Yang, Jin Wang, Yongjia Sheng, Xiaohong Zhou, Heping Shen
Publikováno v:
Journal of Cellular and Molecular Medicine
Our previous study has found that aureusidin can inhibit inflammation by targeting myeloid differentiation 2 (MD2) protein. Structural optimization of aureusidin gave rise to a derivative named CNQX. LPS was used to induce inflammation in intestinal
Autor:
Rui Ding, Jun Zeng, Hongzhu Lv, Enhui Hong, Shizhong Zheng, Zhichong Xie, Yaoming Qu, Jiayu Xie, Liang Feng, Yi-zhao Chen
Publikováno v:
Journal of Cellular and Molecular Medicine
Intracerebral hemorrhage (ICH) can induce intensively oxidative stress, neuroinflammation, and brain cell apoptosis. However, currently, there is no highly effective treatment available. Puerarin (PUE) possesses excellent neuroprotective effects by s
Autor:
Yanhong Zhang, Yi Huang, Shaoxiang Xian, Jiaqi Jin, Yang Chen, Dawei Lian, Jiaying Liu, Ruifang Han, Xiao Wang, Li Zhu
Publikováno v:
Journal of Cellular and Molecular Medicine
In diabetes‐induced complications, inflammatory‐mediated endothelial dysfunction is the core of disease progression. Evidence shows that kakonein, an isoflavone common in Pueraria, can effectively treat diabetes and its complications. Therefore,
Autor:
Hiroko Isoda, Sofya Suidasari, Kenichi Tominaga, Miki Yokozawa, Mohamed Moncef Harrabi, Farhana Ferdousi, Ken Yamauchi, Shinji Kondo
Publikováno v:
Journal of Cellular and Molecular Medicine
Anaemia is one of the leading causes of disability in young adults and is associated with increased morbidity and mortality in elderly. With a global target to reduce the disease burden of anaemia, recent researches focus on novel compounds with the
Autor:
Jinwen Tan, Shuquan Wei, Xiaomei Huang, Weihong Guo, Zhike Liang, Ziwen Zhao, Yujun Li, Hua He, Zexun Mo
Publikováno v:
Journal of Cellular and Molecular Medicine
Long non‐coding ribonucleic acids (lncRNAs) play critical roles in acute lung injury (ALI). We aimed to explore the involvement of lncRNA HOX transcript antisense intergenic ribonucleic acid (HOTAIR) in regulating autophagy in lipopolysaccharide (L
Autor:
Luwen Wang, Yao Wang, Pan Cao, Zuojiong Gong, Qian Chen, Chunxia Shi, Fangzhou Jiao, Maohua Pei
Publikováno v:
Journal of Cellular and Molecular Medicine. 25:7218-7228
Acute liver failure (ALF) is a rare and critical medical condition. This study was designed to investigate the protective effects and underlying mechanism of ACY1215 in ALF mice. Our findings suggested that ACY1215 treatment ameliorates the pathologi
Autor:
Ping Li, Qi Xu, Yan Li, Yi Liu, Honghong Pan, Dongyu Ma, Demin Cheng, Wenqing Sun, Chunhui Ni, Guanru Li
Publikováno v:
Journal of Cellular and Molecular Medicine
Dysregulation of non‐coding RNAs (ncRNAs) has been proved to play pivotal roles in epithelial‐mesenchymal transition (EMT) and fibrosis. We have previously demonstrated the crucial function of long non‐coding RNA (lncRNA) ATB in silica‐induce