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Autor:
Austyn Colter, James Ropa, Melissa L. Fishel, Brian Parkin, Maegan L. Capitano, Heiko Konig, George E. Sandusky, Claudiu T. Supuran, Callista Maguire, Fangli Chen, Daniela N. Petrusca, Max Jacobsen, Xue Wu, H. Scott Boswell, Emilia Licarete, Fabrizio Carta, Magdalena Czader
Publikováno v:
Journal of Cellular and Molecular Medicine
Acute myeloid leukaemia (AML) is an aggressive form of blood cancer that carries a dismal prognosis. Several studies suggest that the poor outcome is due to a small fraction of leukaemic cells that elude treatment and survive in specialised, oxygen (
Publikováno v:
Journal of Cellular and Molecular Medicine
In our previous study, we reported that CELF2 has a tumour‐suppressive function in glioma. Here, we performed additional experiments to elucidate better its role in cancer. The expression profile of CELF2 was analysed by the GEPIA database, and Kap
Publikováno v:
Journal of Cellular and Molecular Medicine
This study aimed to investigate the role and regulatory mechanisms of Ezrin in synovial vessels in rheumatoid arthritis (RA). Synovial tissues were obtained from people with osteoarthritis people and patients with RA patients. We also used an antigen
Publikováno v:
Journal of Cellular and Molecular Medicine
KCTD11 has been reported to be a potential tumour suppressor in several tumour types. However, the expression of KCTD11 and its role has not been reported in human non‐small cell lung cancer (NSCLC). Whether its potential molecular mechanism is rel
Autor:
Zhengyu Zhang, Mulan Jin, Meizhu Xiao, Jing Zhao, Meiying Song, Haiteng Deng, Weihua Li, Huimin Bai, Ruili Jiao
Publikováno v:
Journal of Cellular and Molecular Medicine
Objective The present study was aimed to determine the differentially expressed proteins (DEPs) between paired samples of cervical cancer (CC) and paracancerous tissue by quantitative proteomics and to examine the effects of DUSP7 expression on tumor
Publikováno v:
Journal of Cellular and Molecular Medicine
It has been demonstrated that neural precursor cell expressed developmentally downregulated protein (NEDD) plays crucial roles in tumorigenesis and may serve as potential biomarkers in cancer diagnosis and prognosis. However, few studies systematical
Publikováno v:
Journal of Cellular and Molecular Medicine
Cadherin EGF LAG seven‐pass G‐type receptors (CELSRs) are involved in the progression of various types of cancer. CELSR3, a crucial signalling molecule in the WNT/PCP pathway, is believed to be associated with tumorigenesis and metastasis. Howeve
Autor:
Yixuan Zhang, Guifang Xu, Chenghu Xu, Ying Lv, Borui Li, Hui Wang, Chenglin Lu, Shanhua Bao, Pin Wang, Haochen Su, Siqi Zhou, Yue Yuan, Shu Zhang, Jie Yang, Jing Zhao, Xiaoping Zou, Lei Wang, Xihan Li
Publikováno v:
Journal of Cellular and Molecular Medicine
Pancreatic cancer (PC) has been the fourth cancer‐related death worldwide, diagnosed at an unresectable stage due to its rapid progression and few symptoms of this disease at early stages. The aim of this study was to determine the association betw
Autor:
Da Fu, Pei-Yao Wang, Gao-Ren Wang, Liu Li, Li-Peng Gu, Ji-Bin Liu, Hui-Min Wang, Ping-Sheng Cao, Zhi-Jun Wu, Yu-Shui Ma, Yi Shi, Hong‐Wei Zhang
Publikováno v:
Journal of Cellular and Molecular Medicine
MicroRNA‐24‐3p (miR‐24‐3p) has been implicated as a key promoter of chemotherapy resistance in numerous cancers. Meanwhile, cancer‐associated fibroblasts (CAFs) can secret exosomes to transfer miRNAs, which mediate tumour development. Howev
Autor:
Cao Yueyu, Shanshan Yu, Zeng-Guang Xu, Ma Zuan, Guangxue Wang, Xuelian Fu, Ying Lu, Qinchuan Li
Publikováno v:
Journal of Cellular and Molecular Medicine
Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1), as the key component of the transcription initiation factor complex EIF4F, is significantly upregulated in multiple solid tumours, including lung cancer. However, the function and mechanism