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Autor:
Volker Spindler, Brenda Gerull, Kathleen J. Green, Andrew P. Kowalczyk, Rudolf Leube, Ali J. Marian, Hendrik Milting, Eliane J. Müller, Carien Niessen, Aimee S. Payne, Nicolas Schlegel, Enno Schmidt, Pavel Strnad, Ritva Tikkanen, Franziska Vielmuth, Jens Waschke
Publikováno v:
Journal of cell science. 136(1)
Desmosome diseases are caused by dysfunction of desmosomes, which anchor intermediate filaments (IFs) at sites of cell–cell adhesion. For many decades, the focus of attention has been on the role of actin filament-associated adherens junctions in d
Autor:
Kerstin Hinterndorfer, Marine H. Laporte, Felix Mikus, Lucas Tafur, Clélia Bourgoint, Manoel Prouteau, Gautam Dey, Robbie Loewith, Paul Guichard, Virginie Hamel
Publikováno v:
Journal of Cell Science. 135
The budding and fission yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe have served as invaluable model organisms to study conserved fundamental cellular processes. Although super-resolution microscopy has in recent years paved the way
Autor:
Sarantis Korniotis, Melissa Saichi, Coline Trichot, Caroline Hoffmann, Elise Amblard, Annick Viguier, Sophie Grondin, Floriane Noel, Hamid Mattoo, Vassili Soumelis
Publikováno v:
Journal of Cell Science. 135
T follicular helper (Tfh) cells regulate humoral responses and present a marked phenotypic and functional diversity. Type 1 Tfh (Tfh1) cells were recently identified and associated with disease severity in infection and autoimmune diseases. The cellu
Autor:
David J. Beebe, Rouven Schoppmeyer, Martijn A. Nolte, Jaap D. van Buul, Max Blokker, Lanette Kempers, Abraham C.I. van Steen
Publikováno v:
Journal of cell science, 134(21):jcs258690. Company of Biologists Ltd
Journal of cell science, 134(21):jcs258690, 1-14. Company of Biologists Ltd
J Cell Sci
Van Steen, A C I, Kempers, L, Schoppmeyer, R, Blokker, M, Beebe, D J, Nolte, M A & Van Buul, J D 2021, ' Transendothelial migration induces differential migration dynamics of leukocytes in tissue matrix ', Journal of cell science, vol. 134, no. 21, jcs258690, pp. 1-14 . https://doi.org/10.1242/jcs.258690
Journal of Cell Science, 134(21):jcs258690. Company of Biologists Ltd
van Steen, A C I, Kempers, L, Schoppmeyer, R, Blokker, M, Beebe, D J, Nolte, M A & van Buul, J D 2021, ' Transendothelial migration induces differential migration dynamics of leukocytes in tissue matrix ', Journal of Cell Science, vol. 134, no. 21, jcs258690 . https://doi.org/10.1242/jcs.258690
Journal of cell science, 134(21):jcs258690, 1-14. Company of Biologists Ltd
J Cell Sci
Van Steen, A C I, Kempers, L, Schoppmeyer, R, Blokker, M, Beebe, D J, Nolte, M A & Van Buul, J D 2021, ' Transendothelial migration induces differential migration dynamics of leukocytes in tissue matrix ', Journal of cell science, vol. 134, no. 21, jcs258690, pp. 1-14 . https://doi.org/10.1242/jcs.258690
Journal of Cell Science, 134(21):jcs258690. Company of Biologists Ltd
van Steen, A C I, Kempers, L, Schoppmeyer, R, Blokker, M, Beebe, D J, Nolte, M A & van Buul, J D 2021, ' Transendothelial migration induces differential migration dynamics of leukocytes in tissue matrix ', Journal of Cell Science, vol. 134, no. 21, jcs258690 . https://doi.org/10.1242/jcs.258690
Leukocyte extravasation into inflamed tissue is a complex process that is difficult to capture as a whole in vitro. We employed a blood-vessel-on-a-chip model in which endothelial cells were cultured in a tube-like lumen in a collagen-1 matrix. The v
Autor:
Lucian B. Tomaz, Bernard A. Liu, null Meroshini M, Sheena L. M. Ong, Ee Kim Tan, Nicholas S. Tolwinski, Christopher S. Williams, Anne-Claude Gingras, Marc Leushacke, N. Ray Dunn
Publikováno v:
Journal of Cell Science. 135
The gene mutated in colorectal cancer (MCC) encodes a coiled-coil protein implicated, as its name suggests, in the pathogenesis of hereditary human colon cancer. To date, however, the contributions of MCC to intestinal homeostasis and disease remain
Publikováno v:
Journal of Cell Science. 135
A large group of keratin genes (n=54 in the human genome) code for intermediate filament (IF)-forming proteins and show differential regulation in epithelial cells and tissues. Keratin expression can be highly informative about the type of epithelial
Autor:
Lizbeth Perez-Castro, Niranjan Venkateswaran, Roy Garcia, Yi-Heng Hao, M. C. Lafita-Navarro, Jiwoong Kim, Dagan Segal, Etai Saponzik, Bo-Jui Chang, Reto Fiolka, Gaudenz Danuser, Lin Xu, Thomas Brabletz, Maralice Conacci-Sorrell
Publikováno v:
Journal of Cell Science. 135
The ligand-activated transcription factor aryl hydrocarbon receptor (AHR) regulates cellular detoxification, proliferation and immune evasion in a range of cell types and tissues, including cancer cells. In this study, we used RNA-sequencing to ident
Publikováno v:
Journal of Cell Science. 135
The forkhead box transcription factor FOXQ1 contributes to the pathogenesis of carcinomas. In colorectal cancers, FOXQ1 promotes tumour metastasis by inducing epithelial-to-mesenchymal transition (EMT) of cancer cells. FOXQ1 may exacerbate cancer by
Publikováno v:
Journal of Cell Science. 135
Dictyostelium discoideum is a unicellular eukaryote that eats bacteria, and eventually outgrows the bacteria. D. discoideum cells accumulate extracellular polyphosphate (polyP), and the polyP concentration increases as the local cell density increase
Publikováno v:
Journal of Cell Science. 135
Necroptosis, or programmed necrosis, is an inflammatory form of cell death with important functions in host defense against pathogens and tissue homeostasis. The four cytosolic receptor-interacting protein kinase homotypic interaction motif (RHIM)-co