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Autor:
Melanie C. Ridgway, Daniela Cihalova, Simon H. J. Brown, Phuong Tran, Todd W. Mitchell, Alexander G. Maier
Publikováno v:
Journal of Cell Science. 135
Male and female Plasmodium falciparum gametocytes are the parasite lifecycle stage responsible for transmission of malaria from the human host to the mosquito vector. Not only are gametocytes able to survive in radically different host environments,
Autor:
Laasya Dhandapani, Marion C. Salzer, Juan M. Duran, Gabriele Zaffagnini, Cristian De Guirior, Maria Angeles Martínez-Zamora, Elvan Böke
Publikováno v:
Journal of Cell Science
Oocytes spend the majority of their lifetime in a primordial state. The cellular and molecular biology of primordial oocytes is largely unexplored; yet, it is necessary to study them to understand the mechanisms through which oocytes maintain cellula
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Centromeres are chromosomal regions that serve as sites for kinetochore formation and microtubule attachment, processes that are essential for chromosome segregation during mitosis. Centromeres are almost universally defined by the histone variant CE
Autor:
Stephanie Vlachos, Byoungjoo Yoo, Ryan D. Morin, Lionel Pereira, Krysta M. Coyle, Richard Zapf, Timothy E. Audas, Nicholas Harden, Emma Lacroix, Sahil Chandhok, Dane Marijan
Publikováno v:
Journal of Cell Science. 134
In response to environmental stress, human cells have been shown to form reversible amyloid aggregates within the nucleus, termed amyloid bodies (A-bodies). These protective physiological structures share many of the biophysical characteristics assoc
Autor:
Christopher M. Hammell, Françoise Schwager, Alexandra Bondaz, Jing Wang, Monica Gotta, Simona Abbatemarco
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
Journal of cell science, Vol. 134, No 22 (2021) P. jcs258834
article-version (VoR) Version of Record
Journal of cell science, Vol. 134, No 22 (2021) P. jcs258834
When exposed to stressful conditions, eukaryotic cells respond by inducing the formation of cytoplasmic ribonucleoprotein complexes called stress granules. Here, we use C. elegans to study two proteins that are important for stress granule assembly i
Autor:
Nicolò Ilacqua, Eugene V. Koonin, Irene Anastasia, Katalin Tóth, Andrea Raimondi, Thomas Q. de Aguiar Vallim, Philippe Lemieux, Luca Pellegrini
Publikováno v:
J Cell Sci
Hepatic lipid homeostasis depends on intracellular pathways that respire fatty acid in peroxisomes and mitochondria, and on systemic pathways that secrete fatty acid into the bloodstream, either free or condensed in very-low-density lipoprotein (VLDL
Autor:
Lars Malte Steinbeck, Angeliki Koufali, Ronja Markworth, Vivian Dambeck, Bastian Bues, Carolin Wichmann, Tal M. Dankovich, Katja Burk
Publikováno v:
Journal of Cell Science. 134
Axonal survival and growth requires signalling from tropomyosin receptor kinases (Trks). To transmit their signals, receptor–ligand complexes are endocytosed and undergo retrograde trafficking to the soma, where downstream signalling occurs. Vesicl
Autor:
Simonetta Piatti, Alain Devault
Publikováno v:
Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2021, ⟨10.1242/jcs.258972⟩
Journal of Cell Science, Company of Biologists, 2021, 134 (19), ⟨10.1242/jcs.258972⟩
Journal of Cell Science, Company of Biologists, 2021, ⟨10.1242/jcs.258972⟩
Journal of Cell Science, Company of Biologists, 2021, 134 (19), ⟨10.1242/jcs.258972⟩
At mitotic exit the cell cycle engine is reset to allow crucial processes, such as cytokinesis and replication origin licensing, to take place before a new cell cycle begins. In budding yeast, the cell cycle clock is reset by a Hippo-like kinase casc
Autor:
Takashi Ishikawa, Cornelia Imsand, Anne Greet Bittermann, Elisabeth Müller, Andreas Menzel, Mirko Holler, Manuel Guizar-Sicairos, Christian Grimm, Ana Diaz, Gebhard F. X. Schertler, Valerie Panneels, Andres Kaech
Publikováno v:
Journal of Cell Science. 134
Ptychographic hard X-ray computed tomography (PXCT) is a recent method allowing imaging with quantitative electron-density contrast. Here, we imaged, at cryogenic temperature and without sectioning, cellular and subcellular structures of a chemically
Autor:
Saclier, Marielle, Larbi, Sabrina, Ly, Ha, Moulin, Eugénie, Mounier, Rémi, Chazaud, Bénédicte, Juban, Gaëtan, Ben Larbi, Sabrina, My Ly, Ha
Publikováno v:
Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2021, 134 (18), pp.jcs258429. ⟨10.1242/jcs.258429⟩
Journal of Cell Science, 2021, 134 (18), pp.jcs258429. ⟨10.1242/jcs.258429⟩
Journal of Cell Science, Company of Biologists, 2021, 134 (18), pp.jcs258429. ⟨10.1242/jcs.258429⟩
Journal of Cell Science, 2021, 134 (18), pp.jcs258429. ⟨10.1242/jcs.258429⟩
Duchenne muscular dystrophy is a genetic muscle disease characterized by chronic inflammation and fibrosis mediated by a pro-fibrotic macrophage population expressing pro-inflammatory markers. Our aim was to characterize cellular events leading to th