Zobrazeno 1 - 10
of 20
pro vyhledávání: ''
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Centromeres are chromosomal regions that serve as sites for kinetochore formation and microtubule attachment, processes that are essential for chromosome segregation during mitosis. Centromeres are almost universally defined by the histone variant CE
Autor:
Karina Simantov, Ron Dzikowski, Yotam Kaufman, Brajesh Kumar Singh, Manish Goyal, Shiri Eshar
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Plasmodium falciparum, the parasite responsible for the deadliest form of human malaria, replicates within the erythrocytes of its host, where it encounters numerous pressures that cause extensive DNA damage, which must be repaired efficiently to ens
Autor:
Vera Schwarz, Katarzyna Majstrowicz, Stefanie J. Oeding, Ulrike Honnert, Petra Nikolaus, Martin Bähler, Sandra A. Hemkemeyer
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Myosin XIX (Myo19) is an actin-based motor that competes with adaptors of microtubule-based motors for binding to the outer mitochondrial transmembrane proteins Miro1 and Miro2 (collectively Miro, also known as RhoT1 and RhoT2, respectively). Here, w
Autor:
Folma Buss, Antonina J. Kruppa
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Mitochondria are multifunctional organelles that not only produce energy for the cell, but are also important for cell signalling, apoptosis and many biosynthetic pathways. In most cell types, they form highly dynamic networks that are constantly rem
Autor:
Mirjana Malnar, Boris Rogelj
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The expanded GGGGCC repeat mutation in the C9orf72 gene is the most common genetic cause of the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The expansion is transcribed to sense and antisense RNA,
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
A multiprotein complex containing TACC3, clathrin and other proteins has been implicated in mitotic spindle stability. To disrupt this complex in an anti-cancer context, we need to understand its composition and how it interacts with microtubules. In
Autor:
Daphne M. van Elsland, Sabine A.G. Cuijpers, William C. Earnshaw, Jan G. Ruppert, Alfred C.O. Vertegaal, Edwin Willemstein
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
Journal of Cell Science, 133(14). COMPANY BIOLOGISTS LTD
Cuijpers, S, Willemstein, E, Ruppert, J, van Elsland, D M, Earnshaw, B & Vertegaal, A C O 2020, ' Chromokinesin KIF4A teams up with Stathmin 1 to regulate abscission in a SUMO-dependent manner ', Journal of Cell Science . https://doi.org/10.1242/jcs.248591
article-version (VoR) Version of Record
Journal of Cell Science, 133(14). COMPANY BIOLOGISTS LTD
Cuijpers, S, Willemstein, E, Ruppert, J, van Elsland, D M, Earnshaw, B & Vertegaal, A C O 2020, ' Chromokinesin KIF4A teams up with Stathmin 1 to regulate abscission in a SUMO-dependent manner ', Journal of Cell Science . https://doi.org/10.1242/jcs.248591
Cell division ends when two daughter cells physically separate via abscission, the cleavage of the intercellular bridge. It is not clear how the anti-parallel microtubule bundles bridging daughter cells are severed. Here, we present a novel abscissio
Publikováno v:
Journal of Cell Science. 131(JCS215442):1-10
Macroautophagy (simply called autophagy hereafter) is an intracellular degradation mechanism that is activated by nutrient starvation. Although it is well known that starvation induces autophagosome formation in an mTORC1-dependent manner, whether st
Autor:
Mark Marsh, Annegret Pelchen-Matthews, David O. Nkwe, Jemima J. Burden, Raffaella Carzaniga, Thomas R. Lerner, Anne Weston, Joanne Durgan, Maximiliano G. Gutierrez, Martin L. Jones, Lucy M. Collinson, Marie-Charlotte Domart, Matthew R. G. Russell, Oliver Florey, Christopher J. Peddie
Publikováno v:
Journal of Cell Science
The processes of life take place in multiple dimensions, but imaging these processes in even three dimensions is challenging. Here, we describe a workflow for 3D correlative light and electron microscopy (CLEM) of cell monolayers using fluorescence m
Publikováno v:
Journal of Cell Science
Growth factor-induced signal transduction pathways are tightly regulated at multiple points intracellularly, but how cells monitor levels of extracellular ligand and translate this information into appropriate downstream responses remains unclear. Un