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Autor:
Adwiteeya Misra, Cameron D. Baker, Elizabeth M. Pritchett, Kimberly N. Burgos Villar, John M. Ashton, Eric M. Small
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 9, Iss 1, p 1 (2022)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease; Volume 9; Issue 1; Pages: 1
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease; Volume 9; Issue 1; Pages: 1
The neonatal mammalian heart exhibits a remarkable regenerative potential, which includes fibrotic scar resolution and the generation of new cardiomyocytes. To investigate the mechanisms facilitating heart repair after apical resection in neonatal mi
Autor:
Adam D. Langenbacher, Fei Lu, Lauren Crisman, Zi Yi Stephanie Huang, Douglas J. Chapski, Thomas M. Vondriska, Yibin Wang, Chen Gao, Jau-Nian Chen
Publikováno v:
Journal of cardiovascular development and disease, vol 10, iss 5
Journal of Cardiovascular Development and Disease; Volume 10; Issue 5; Pages: 221
Journal of Cardiovascular Development and Disease; Volume 10; Issue 5; Pages: 221
The PAF1 complex component Rtf1 is an RNA Polymerase II-interacting transcription regulatory protein that promotes transcription elongation and the co-transcriptional monoubiquitination of histone 2B. Rtf1 plays an essential role in the specification
Publikováno v:
Journal of Cardiovascular Development and Disease; Volume 9; Issue 10; Pages: 321
Atrial septal defect (ASD) is one of the most common forms of congenital heart disease (CHD). Genetic variants in the coding region of the CITED2 gene are known to be significantly correlated with CHD, but the role of variants in the promoter region
Autor:
Suyon Chang, Jinho Park, Young-Joong Yang, Kyongmin Sarah Beck, Pan Ki Kim, Byoung Wook Choi, Jung Im Jung
Publikováno v:
Journal of Cardiovascular Development and Disease; Volume 9; Issue 8; Pages: 271
Background: Myocardial T2* mapping at 1.5T remains the gold standard, but the use of 3T scanners is increasing. We aimed to determine the conversion equations in different scanners with clinically available, vendor-provided T2* mapping sequences usin
Publikováno v:
Journal of Cardiovascular Development and Disease; Volume 9; Issue 8; Pages: 266
Background: The present study investigated whether angiotensin II type 1 receptor blocker irbesartan (ARB) and partial agonist of PPAR-γ prevents heart apoptosis by suppressing cardiac Fas/FasL-mediated to mitochondria-mediated apoptosis in the hear
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 21, p 21 (2021)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease
Heart disease remains the single largest cause of death in developed countries, and novel therapeutic interventions are desperately needed to alleviate this growing burden. The cardiac lymphatic system is the long-overlooked counterpart of the corona
Autor:
Mohamed Nemir, Maryam Kay, Damien Maison, Corinne Berthonneche, Alexandre Sarre, Isabelle Plaisance, Thierry Pedrazzini
Publikováno v:
Journal of Cardiovascular Development and Disease; Volume 9; Issue 4; Pages: 111
Cardiac pathologies lead to an acute or gradual loss of cardiomyocytes. Because of the limited regenerative capacity of the mammalian heart, cardiomyocytes are only replaced by fibrotic tissue. Excessive fibrosis contributes to the deterioration of c
Autor:
Neha Ahuja, Paige Ostwald, Alex Gendernalik, Elena Guzzolino, Letizia Pitto, David Bark, Deborah M. Garrity
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 9, Iss 22, p 22 (2022)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease; Volume 9; Issue 1; Pages: 22
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease; Volume 9; Issue 1; Pages: 22
Heart valve development is governed by both genetic and biomechanical inputs. Prior work has demonstrated that oscillating shear stress associated with blood flow is required for normal atrioventricular (AV) valve development. Cardiac afterload is de
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 6, Iss 4, p 39 (2019)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease, MDPI, 2019, 6 (4), pp.39. ⟨10.3390/jcdd6040039⟩
Journal of Cardiovascular Development and Disease, 2019, 6 (4), pp.39. ⟨10.3390/jcdd6040039⟩
Volume 6
Issue 4
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease, MDPI, 2019, 6 (4), pp.39. ⟨10.3390/jcdd6040039⟩
Journal of Cardiovascular Development and Disease, 2019, 6 (4), pp.39. ⟨10.3390/jcdd6040039⟩
Volume 6
Issue 4
Among the aortic valve diseases, the bicuspid aortic valve (BAV) occurs when the aortic valve has two leaflets (cusps), rather than three, and represents the most common form of congenital cardiac malformation, affecting 1&ndash
2% of the popula
2% of the popula
Autor:
Nicola M Blythe, Neil A. Turner
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 6, Iss 3, p 27 (2019)
Journal of cardiovascular development and disease
Journal of Cardiovascular Development and Disease
Journal of cardiovascular development and disease
Journal of Cardiovascular Development and Disease
The cardiac fibroblast is a remarkably versatile cell type that coordinates inflammatory, fibrotic and hypertrophic responses in the heart through a complex array of intracellular and intercellular signaling mechanisms. One important signaling node t