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Autor:
Shuyi Nie
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 2, p 51 (2023)
A frog is a classical model organism used to uncover processes and regulations of early vertebrate development, including heart development. Recently, we showed that a frog also represents a useful model to study a rare human congenital heart disease
Externí odkaz:
https://doaj.org/article/ec11a2bdaf874e02b3ac2e73f2bff7e6
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 9, Iss 5, p 152 (2022)
Significant surgical and medical advances over the past several decades have resulted in a growing number of infants and children surviving with hypoplastic left heart syndrome (HLHS) and other congenital heart defects associated with a single system
Externí odkaz:
https://doaj.org/article/48a35e960bb54a1e83b4bc200a8fae38
Autor:
Melissa Anfinson, Robert H. Fitts, John W. Lough, Jeanne M. James, Pippa M. Simpson, Stephanie S. Handler, Michael E. Mitchell, Aoy Tomita-Mitchell
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 9, Iss 5, p 144 (2022)
Hypoplastic left heart syndrome (HLHS) is a severe congenital heart disease (CHD) with complex genetic inheritance. HLHS segregates with other left ventricular outflow tract (LVOT) malformations in families, and can present as either an isolated phen
Externí odkaz:
https://doaj.org/article/e50f563e1d3d475dabbd72b5ee91d6f6
Autor:
Jeanne L. Theis, Timothy M. Olson
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 9, Iss 4, p 117 (2022)
Hypoplastic left heart syndrome (HLHS) is a genetically complex disorder. Whole genome sequencing enables comprehensive scrutiny of single nucleotide variants and small insertions/deletions, within both coding and regulatory regions of the genome, re
Externí odkaz:
https://doaj.org/article/26a54651c0f44795a81f26220957a3b1
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 3, Iss 3, p 24 (2016)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease
For more than a decade, stem cell therapy has been the focus of intensive efforts for the treatment of adult heart disease, and now has promise for treating the pediatric population. On the basis of encouraging results in the adult field, the applica