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Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 7, p 305 (2023)
Epigenetic marks regulate the transcriptomic landscape by facilitating the structural packing and unwinding of the genome, which is tightly folded inside the nucleus. Lysine-specific histone methylation is one such mark. It plays crucial roles during
Externí odkaz:
https://doaj.org/article/9e430acb22bd4ca8b1779f0060e00d00
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 2, p 78 (2023)
Background: Congenital heart disease (CHD) is one of the most predominant birth defects that causes infant death worldwide. The timely and successful surgical treatment of CHD on newborns after delivery requires accurate detection and reliable diagno
Externí odkaz:
https://doaj.org/article/1bd68b76e8694b35b5e4ead7d5a9df25
Akademický článek
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Autor:
Joshua C. Peterson, Tim P. Kelder, Marie José T. H. Goumans, Monique R. M. Jongbloed, Marco C. DeRuiter
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 5, p 47 (2021)
Whilst knowledge regarding the pathophysiology of congenital heart disease (CHDs) has advanced greatly in recent years, the underlying developmental processes affecting the cardiac outflow tract (OFT) such as bicuspid aortic valve, tetralogy of Fallo
Externí odkaz:
https://doaj.org/article/9b39efbce8554f41b7be1b1e590c566e
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 7, Iss 2, p 22 (2020)
Left-sided congenital heart defects (CHDs) are among the most common forms of congenital heart disease, but a disease-causing gene has only been identified in a minority of cases. Here, we identified a candidate gene for CHDs, KIF1A, that was associa
Externí odkaz:
https://doaj.org/article/2884066d6d1f47eb9dde89a56175c542
Autor:
Monique Y. Rennie, Stephanie Stovall, James P. Carson, Michael Danilchik, Kent L. Thornburg, Sandra Rugonyi
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 4, Iss 4, p 24 (2017)
Blood flow is critical for normal cardiac development. Hemodynamic stimuli outside of normal ranges can lead to overt cardiac defects, but how early heart tissue remodels in response to altered hemodynamics is poorly understood. This study investigat
Externí odkaz:
https://doaj.org/article/9bf56633ae904471b121655ccfe5d602
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 3, Iss 1, p 1 (2015)
We analyzed heart wall motion and blood flow dynamics in chicken embryos using in vivo optical coherence tomography (OCT) imaging and computational fluid dynamics (CFD) embryo-specific modeling. We focused on the heart outflow tract (OFT) region of d
Externí odkaz:
https://doaj.org/article/66574fb813ca45fb900849053a691824