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Autor:
Amanda Pinheiro, Francisco J. Naya
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 84, p 84 (2021)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease
Non-coding RNAs (ncRNAs) play a key role in the regulation of transcriptional and epigenetic activity in mammalian cells. Comprehensive analysis of these ncRNAs has revealed sophisticated gene regulatory mechanisms which finely tune the proper gene o
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 89, p 89 (2021)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease
The neural crest (NC) is a multipotent and temporarily migratory cell population stemming from the dorsal neural tube during vertebrate embryogenesis. Cardiac neural crest cells (NCCs), a specified subpopulation of the NC, are vital for normal cardio
Autor:
Laura A. Dyer, Sandra Rugonyi
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 90, p 90 (2021)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease
In congenital heart disease, the presence of structural defects affects blood flow in the heart and circulation. However, because the fetal circulation bypasses the lungs, fetuses with cyanotic heart defects can survive in utero but need prompt inter
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 52, p 52 (2021)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease
Connexin (Cx43)-formed channels have been linked to cardiac arrhythmias and diseases of the heart associated with myocardial tissue loss and fibrosis. These pathologies include ischemic heart disease, ischemia-reperfusion injury, heart failure, hyper
Autor:
Tahir Ahmad Mir, Ajaz Ahmad Waza, Mohammad Muzaffar Mir, Mohsin Maqbool, Babar Mohammad, Shamsu Nisa, Imadeldin Elfaki, Faisel M. Abu-Duhier, Rashid Mir, Chandan Jha, Naina Khullar, Salem Owaid Albalawi, Jameel Barnawi
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 22, p 22 (2021)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease
Cardiovascular diseases are the leading cause of death worldwide in different cohorts. It is well known that miRNAs have a crucial role in regulating the development of cardiovascular physiology, thus impacting the pathophysiology of heart diseases.
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 21, p 21 (2021)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease
Heart disease remains the single largest cause of death in developed countries, and novel therapeutic interventions are desperately needed to alleviate this growing burden. The cardiac lymphatic system is the long-overlooked counterpart of the corona
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 7, Iss 30, p 30 (2020)
Journal of Cardiovascular Development and Disease
Journal of cardiovascular development and disease, vol 7, iss 3
Journal of Cardiovascular Development and Disease
Journal of cardiovascular development and disease, vol 7, iss 3
Traditionally, gross cardiac anatomy has been described mainly based on the findings in the dissection suite. Analyses of heart specimens have contributed immensely towards building a fundamental knowledge of cardiac anatomy. However, there are limit
Autor:
Nicola M Blythe, Neil A. Turner
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 6, Iss 3, p 27 (2019)
Journal of cardiovascular development and disease
Journal of Cardiovascular Development and Disease
Journal of cardiovascular development and disease
Journal of Cardiovascular Development and Disease
The cardiac fibroblast is a remarkably versatile cell type that coordinates inflammatory, fibrotic and hypertrophic responses in the heart through a complex array of intracellular and intercellular signaling mechanisms. One important signaling node t
Autor:
Christine B. Kern
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 92, p 92 (2021)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease
A bicuspid aortic valve (BAV) is the most common cardiac malformation, found in 0.5% to 2% of the population. BAVs are present in approximately 50% of patients with severe aortic stenosis and are an independent risk factor for aortic aneurysms. Curre
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 42, p 42 (2021)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease, 2021, 8 (4), pp.42. ⟨10.3390/jcdd8040042⟩
Journal of Cardiovascular Development and Disease, MDPI, 2021, 8 (4), pp.42. ⟨10.3390/jcdd8040042⟩
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease, 2021, 8 (4), pp.42. ⟨10.3390/jcdd8040042⟩
Journal of Cardiovascular Development and Disease, MDPI, 2021, 8 (4), pp.42. ⟨10.3390/jcdd8040042⟩
International audience; Anomalies in the cardiac outflow tract (OFT) are among the most frequent congenital heart defects (CHDs). During embryogenesis, the cardiac OFT is a dynamic structure at the arterial pole of the heart. Heart tube elongation oc