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Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 3, Iss 2, p 19 (2016)
Journal of Cardiovascular Development and Disease; Volume 3; Issue 2; Pages: 19
Journal of Cardiovascular Development and Disease; Volume 3; Issue 2; Pages: 19
Valosin-containing protein (VCP) is a highly conserved mechanoenzyme that helps maintain protein homeostasis in all cells and serves specialized functions in distinct cell types. In skeletal muscle, it is critical for myofibrillogenesis and atrophy.
Autor:
Francisco J. Naya, Cody A. Desjardins
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 3, Iss 3, p 26 (2016)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease
Proper formation of the mammalian heart requires precise spatiotemporal transcriptional regulation of gene programs in cardiomyocytes. Sophisticated regulatory networks have evolved to not only integrate the activities of distinct transcription facto
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 3, Iss 2, p 14 (2016)
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease
Cardiac transcription factors orchestrate the complex cellular and molecular events required to produce a functioning heart. Misregulation of the cardiac transcription program leads to embryonic developmental defects and is associated with human cong