Zobrazeno 1 - 10
of 26
pro vyhledávání: '"11"'
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 14, Iss 10, Pp 622-627 (2018)
Aim: This study aimed to investigate the key transcription factors (TFs), long noncoding RNAs (lncRNAs), and microRNAs (miRNAs) associated with hepatocellular carcinoma (HCC). Materials and Methods: The datasets GSE31383 and GSE54238 were downloaded
Autor:
Daliang Qi, Liang Xin, Jie Xu, Ye Tian, Yan Cui, Xin Angelique Qi, Yan-zhuo Yang, Chongbiao Huang, Qing-Sheng Wang
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 11, Iss 5, Pp 32-37 (2015)
Background: To evaluate the role of nimotuzumab in combination with chemotherapy in patients with advanced nonsmall cell lung cancer (NSCLC) through progress-free survival, changes in tumor marker expression and adverse drug reactions. Materials and
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 11, Iss 4, Pp 887-892 (2015)
Background: The objective of our study was to explore the characteristics of the regulatory network after siRNA-Sp1 (Specificity Protein 1) treatment in HeLa cells through the regulation network construction with bioinformatics methods. Materials and
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 11, Iss 2, Pp 420-425 (2015)
Aims: To identify key genes and pathways in the development of esophageal squamous cell carcinoma with RNA-seq data. Materials and Methods: RNA-seq data including three paired samples were downloaded from Sequence Read Archive database under accessio
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 11, Iss 1, Pp 158-163 (2015)
Objectives: The purpose of this study was to evaluate the level of expression of the BRCA1 and BRCA2 proteins in sporadic breast cancer cases to determine the functional role of these genes in breast carcinogenesis. Materials and Methods: Paraffin em
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 11, Iss 5, Pp 1-6 (2015)
Lung cancer (LC) is the leading cause of cancer-related deaths worldwide. MicroRNAs (miRNAs) are highly evolutionarily conserved noncoding small RNAs, which were first identified in Caenorhabditis elegans. There are 1100 or more miRNAs have been iden
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 11, Iss 1, Pp 78-82 (2015)
Background: Tumor markers are the substances, which quantitatively change in serum, during tumor development. Tumor markers have now been introduced in the diagnosis of malignant lesions. One such tumor marker is serum lactate dehydrogenase (LDH). In
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 11, Iss 1, Pp 18-23 (2015)
Doxorubicin (Adriamycin, ADM) is an antimitotic drug used in the treatment of a wide range of malignant tumors, including acute leukemia, lymphoma, osteosarcoma, breast cancer, and lung cancer. Multidrug resistance-associated proteins (MRPs) are memb
Autor:
Abdul Aziz Mohamed Yusoff
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 11, Iss 3, Pp 535-544 (2015)
Brain tumor is molecularly a heterogeneous group of diseases, and genetic factors seem to play a crucial role in its genesis. Even though multiple alterations in the nuclear-encoded genes such as tumor suppressor and oncogenes are believed to play a
Caspase-mediated crosstalk between autophagy and apoptosis: Mutual adjustment or matter of dominance
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 11, Iss 3, Pp 514-524 (2015)
In the last decade, it has been well established that programmed cell death (PCD) is not confined to apoptosis (type-I PCD) but cells may use different mechanisms of active self-destruction. One such mechanism is autophagy also called as type-II PCD,