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pro vyhledávání: '"J Aitken"'
Autor:
Brendan E.L. Adams, Damian E. Myers, Mark A. Kirkland, Geoffrey C. Nicholson, C. J. Aitken, Carolina M. Lopez, Jason M. Hodge, Caryll M Waugh
Publikováno v:
Journal of Bone and Mineral Research. 19:190-199
Human osteoclasts can be efficiently generated in vitro from cord blood mononuclear cells and derived CFU-GM colonies. However, CFU-M colonies are poorly osteoclastogenic. Short-term (2–48 h) treatment with GM-CSF stimulates osteoclast formation by
Autor:
Damian E. Myers, Geoffrey C. Nicholson, Jason M. Hodge, Nigel Alexander Morrison, Tanya Vaughan, C. J. Aitken
Publikováno v:
Journal of Bone and Mineral Research. 18:S175-S285
Using gene array analysis, we found that thioredoxin (TRX) binding protein-2 (TBP-2) was down-regulated during osteoclast (OC) differentiation. TBP-2 is a negative regulator of TRX, a small protein with a redox-active dithiol active site. TRX enhance