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Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-22 (2021)
Journal of Biomedical Science
Journal of Biomedical Science
Bipolar disorder is a decidedly heterogeneous and multifactorial disease, with a high individual and societal burden. While not all patients display overt markers of elevated inflammation, significant evidence suggests that aberrant immune signaling
Autor:
Shih Ming Jung, Michael Hsiao, Min Che Tung, Ming Huang Chen, Chun Nan Yeh, Ming Hsien Chien, Yi Chieh Yang, Yi Hua Jan, Tsung Ching Lai, Wei Ming Chang
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-14 (2021)
Journal of Biomedical Science
Journal of Biomedical Science
Background Due to the difficulties in early diagnosing and treating hepatocellular carcinoma (HCC), prognoses for patients remained poor in the past decade. In this study, we established a screening model to discover novel prognostic biomarkers in HC
Autor:
Meng-Shiue Wu, Wei-Zhan Zhuang, Yi-Heng Lin, Huan-Cheng Chang, Thai-Yen Ling, Yen Hua Huang, Long-Jyun Su, Han-Yin Jeng
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-38 (2021)
Journal of Biomedical Science
Journal of Biomedical Science
Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy because of their high immunomodulation ability, tropism towards inflamed and injured tissues, and their easy access and isolation. Currently, there are more than 12
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-16 (2021)
Journal of Biomedical Science
Journal of Biomedical Science
A brain organoid is a self-organizing three-dimensional tissue derived from human embryonic stem cells or pluripotent stem cells and is able to simulate the architecture and functionality of the human brain. Brain organoid generation methods are abun
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-20 (2020)
Journal of Biomedical Science
Journal of Biomedical Science
Monoclonal antibodies (mAbs) are a major targeted therapy for malignancies, infectious diseases, autoimmune diseases, transplant rejection and chronic inflammatory diseases due to their antigen specificity and longer half-life than conventional drugs
Autor:
William Mullen, Agnieszka Latosinska, Michael P. Manns, Jochen Metzger, Martha M. Kirstein, Torsten Voigtländer, Martin Pejchinovski, Harald Mischak, Thorsten Book, Maria Frantzi, Holger Husi
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-14 (2020)
Journal of Biomedical Science
Journal of Biomedical Science
Background Detection of cholangiocarcinoma (CCA) remains a diagnostic challenge. We established diagnostic peptide biomarkers in bile and urine based on capillary electrophoresis coupled to mass spectrometry (CE-MS) to detect both local and systemic
Autor:
Chien-Hsiun Chen, Jer-Yuarn Wu, Ying Ju Lin, Fuu Jen Tsai, Henry Sung Ching Wong, Wei Chiao Chang, Hsing Fang Lu, Wen Ling Liao
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-12 (2019)
Journal of Biomedical Science
Journal of Biomedical Science
Background Genetic factors, dysregulation in the endocrine system, cytokine and paracrine factors are implicated in the pathogenesis of familial short stature (FSS). Nowadays, the treatment choice for FSS is limited, with only recombinant human growt
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-13 (2019)
Journal of Biomedical Science
Journal of Biomedical Science
In many solid tumor types, tumor-associated macrophages (TAMs) are important components of the tumor microenvironment (TME). Moreover, TAMs infiltration is strongly associated with poor survival in solid tumor patients. In this review, we describe th
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-11 (2019)
Journal of Biomedical Science
Journal of Biomedical Science
Enterovirus A71 (EV-A71) is one of the common causative pathogens for hand foot and mouth disease (HFMD) affecting young children. HFMD outbreak can result in a substantial pediatric hospitalization and burden the healthcare services, especially in l
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-10 (2019)
Journal of Biomedical Science
Journal of Biomedical Science
Enterovirus A71 (EV-A71) is an important emerging virus posing a threat to children under five years old. EV-A71 infection in infants or young children can cause hand-foot-and-mouth disease, herpangina, or severe neurological complications. However,