Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yong J. Lee"'
Publikováno v:
Journal of Biological Chemistry. 286:20087-20099
Here, we demonstrate that troglitazone (Rezulin), a peroxisome proliferator-activated receptor agonist, acted in synergy with heregulin to induce massive cell death in breast cancer cells. Although the combination of heregulin and troglitazone (HRG/T
Publikováno v:
Journal of Biological Chemistry. 282:319-328
Previous studies have shown that repeated application of TRAIL induces acquired resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Using human prostate adenocarcinoma DU-145 and human pancreatic carcinoma MiaPaCa-2 cells a
Autor:
Jae J. Song, Yong J. Lee
Publikováno v:
Journal of Biological Chemistry. 280:26845-26855
We have previously observed that glucose deprivation activates the ASK1-MEK-MAPK signal transduction pathway. In the present study, we reveal that two scaffolding proteins, JIP1 and JIP3, have a cross-talk that leads to the regulation of the ASK1-SEK
Autor:
Jedrzej Antosiewicz, Yan Zeng, Sanjay K. Srivastava, Karen L. Lew, Hui Xiao, Yong J. Lee, Dong Xiao, Simon C. Watkins, Anna Herman-Antosiewicz, Shivendra V. Singh, Donald L. Trump, Candace S. Johnson, Sunga Choi
Publikováno v:
Journal of Biological Chemistry. 280:19911-19924
We have shown previously that sulforaphane (SFN), a constituent of many edible cruciferous vegetables including broccoli, suppresses growth of prostate cancer cells in culture as well as in vivo by causing apoptosis, but the sequence of events leadin
Autor:
Jae J. Song, Yong J. Lee
Publikováno v:
Journal of Biological Chemistry. 279:30573-30578
The cellular target responsible for the nuclear export of Daxx has been identified as chromosomal region maintenance 1 (CRM1), which is a carrier protein for nuclear export and a receptor for the nuclear export signal (NES) of Daxx. Binding of Daxx t
Autor:
Juong G. Rhee, Susan A. Walsh, Jae J. Song, Yong J. Lee, Douglas R. Spitz, Mohan Suntharalingam
Publikováno v:
Journal of Biological Chemistry. 277:46566-46575
Epitope-tagged glutaredoxin (GRX) was utilized to determine the role of GRX in oxidative stress-induced signaling and cytotoxicity in glucose-deprived human cancer cells (MCF-7/ADR and DU-145). GRX-overexpressing cells demonstrated resistance to gluc
Autor:
Peter M. Corry, Yong J. Lee
Publikováno v:
Journal of Biological Chemistry. 273:29857-29863
In previous reports we demonstrated that glucose deprivation induces metabolic oxidative stress in drug-resistant human breast carcinoma MCF-7/ADR cells (Lee, Y. J., Galoforo, S. S., Berns, c. M., Chen, J. C., Davis, B. H., Swim, J. E., Corry, P. M.,
Autor:
Peter M. Corry, Geza Erdos, Christine M. Berns, Yong J. Lee, Sandra Galoforo, Anjali K. Gupta, D. K. Ways
Publikováno v:
Journal of Biological Chemistry. 270:28790-28796
We studied the effect of ionizing radiation on the activation of the AP-1 transcription factors and the regulation of basic fibroblast growth factor (bFGF) gene expression in drug-sensitive human breast carcinoma (MCF-7) cells and its drug-resistant