Zobrazeno 1 - 10
of 39
pro vyhledávání: '"HUA HUANG"'
Autor:
Yen-Hua Huang1, Zhihao Jiang1, Qingdan Du1, Kuok Yap1, Bigot, Aurélien2, Kaas, Quentin1, Wang, Conan K.1, Craik, David J.1 d.craik@imb.uq.edu.au
Publikováno v:
Journal of Biological Chemistry. Mar2024, Vol. 300 Issue 3, p1-8. 8p.
Autor:
Qingdan Du, Lai Yue Chan, Anjaneya S. Ravipati, Nicholas D. Condon, David J. Craik, Quentin Kaas, Sónia Troeira Henriques, Edward K. Gilding, Yen-Hua Huang
Publikováno v:
J Biol Chem
Cyclotides are plant-derived peptides characterized by an ∼30-amino acid–long cyclic backbone and a cystine knot motif. Cyclotides have diverse bioactivities, and their cytotoxicity has attracted significant attention for its potential anticancer
Autor:
Tien T. Dang1, Yen-Hua Huang1, Ott, Stanislav2, Harvey, Peta J.1, Gilding, Edward K.1, Tombling, Benjamin J.1, Lai Y. Chan1, Kaas, Quentin1, Claridge-Chang, Adam2,3,4, Craik, David J.1 d.craik@imb.uq.edu.au
Publikováno v:
Journal of Biological Chemistry. Oct2022, Vol. 298 Issue 10, p1-11. 11p.
Publikováno v:
Journal of Biological Chemistry. 298:101822
Cyclotides have a wide range of bioactivities relevant for agricultural and pharmaceutical applications. This large family of naturally occurring macrocyclic peptides is divided into three subfamilies, with the bracelet subfamily being the largest an
Autor:
Yong Zhang, Yanhong Zhao, Xiaochen Kou, Chenfei Wang, Jiayu Chen, Kai Xu, Hong Wang, Linfeng Zhang, Zhenzhen Hou, Wenqiang Liu, Xia Chen, Yi-Wen Xu, Jingyi Li, Hui Yang, Fengchao Wang, Baodong Liu, Yuanlin He, Hua Huang, Yawei Gao, Kun Zhao, Shaorong Gao, Hailin Wang, Jing Li, Heng-Yu Fan
Publikováno v:
Journal of Biological Chemistry. 292:1798-1807
Sall4 (Splat-like 4) plays important roles in maintaining pluripotency of embryonic stem cells and in various developmental processes. Here, we find that Sall4 is highly expressed in oocytes and early embryos. To investigate the roles of SALL4 in oog
Autor:
Lai Yue Chan, Yen-Hua Huang, K. Johan Rosengren, David J. Craik, Jason Mulvenna, Chia Chia Tan, Ching-I Anderson Wang, Christina I. Schroeder, Soohyun Kwon, Xinying Jia
Publikováno v:
Journal of Biological Chemistry. 289:6627-6638
Disulfide-rich cyclic peptides have generated great interest in the development of peptide-based therapeutics due to their exceptional stability toward chemical, enzymatic, or thermal attack. In particular, they have been used as scaffolds onto which
Autor:
Michael Hsiao, Shau-Ping Lin, Kuo-I Lin, Hung-Chih Kuo, Ching-Yu Chuang, Lee Stone, Yen Hua Huang, Hong Nerng Ho, Hsin Fu Chen
Publikováno v:
Journal of Biological Chemistry. 287:14389-14401
The establishment of an effective germ cell selection/enrichment platform from in vitro differentiating human embryonic stem cells (hESCs) is crucial for studying the molecular and signaling processes governing human germ cell specification and devel
Autor:
Roza Nurieva, Xiaopeng Qi, Renren Wen, Stephanie S. Watowich, Junmei Wang, Hua Huang, Mei Yu, Andrei Alekseev, Chen Dong, Yuhong Chen, Haiyan S. Li, Demin Wang, Hai Qi, Andrew Podd
Publikováno v:
Journal of Biological Chemistry. 287:11234-11239
Recent work has identified a new subset of CD4(+) T cells named as Tfh cells that are localized in germinal centers and critical in germinal center formation. Tfh cell differentiation is regulated by IL-6 and IL-21, possibly via STAT3 factor, and B c
Autor:
David J. Craik, Yen-Hua Huang, Gilda Tachedjian, Norelle L. Daly, Adam Johnson, Secondo Sonza, Henri G. Franquelim, Sónia Troeira Henriques, K. Johan Rosengren, Miguel A. R. B. Castanho, Filomena A. Carvalho
Publikováno v:
Journal of Biological Chemistry. 286:24231-24241
Cyclotides, a large family of cyclic peptides from plants, have a broad range of biological activities, including insecticidal, cytotoxic, and anti-HIV activities. In all of these activities, cell membranes seem likely to be the primary target for cy
Publikováno v:
Journal of Biological Chemistry. 286:16063-16073
Basophils mediate many of their biological functions by producing IL-4. However, it is unknown how the Il4 gene is regulated in basophils. Here, we report that CCAAT/enhancer-binding protein α (C/EBPα), a major myeloid transcription factor, was hig