Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Cheryl H. Arrowsmith"'
Autor:
Cheryl H. Arrowsmith, Y. George Zheng, Houjian Cai, Xiangkun Yang, Sunjoo Kim, Michael G. Bartlett, Yingming Zhao, Xiang-Jiao Yang, Zhen Han, Hong Wu, Peter Brown, Qianjin Li, Aiping Dong, Hong Zeng, He Huang
Publikováno v:
Journal of Biological Chemistry. 293:3410-3420
Short-chain acylation of lysine residues has recently emerged as a group of reversible posttranslational modifications in mammalian cells. The diversity of acylation further broadens the landscape and complexity of the proteome. Identification of reg
Autor:
Sandra K. Weller, Alexandra Pozhidaeva, Cheryl H. Arrowsmith, Kareem N. Mohni, Irina Bezsonova, Dmitry M. Korzhnev, Sirano Dhe-Paganon
Publikováno v:
Journal of Biological Chemistry. 290:22907-22918
Human ubiquitin-specific protease 7 (USP7) is a deubiquitinating enzyme that prevents protein degradation by removing polyubiquitin chains from its substrates. It regulates the stability of a number of human transcription factors and tumor suppressor
Autor:
Henry M. Krause, Jiho Yoo, Sunggeon Ko, Hyun Soo Cho, Cheryl H. Arrowsmith, Kwang Min Choe, Weontae Lee, Ji Hye Yun, Iksoo Chang, Hyeyon Kim, Heidi M. Sampson
Publikováno v:
Journal of Biological Chemistry. 286:31225-31231
The interaction between the orphan nuclear receptor FTZ-F1 (Fushi tarazu factor 1) and the segmentation gene protein FTZ is critical for specifying alternate parasegments in the Drosophila embryo. Here, we have determined the structure of the FTZ-F1
Autor:
John Evgueni Vlassov, Sirano Dhe-Paganon, Yi Sheng, Ian Engson, Brian Raught, Shili Duan, Jonathan Shloush, Cheryl H. Arrowsmith, Vivian Saridakis
Publikováno v:
Journal of Biological Chemistry. 286:4796-4808
The tumor suppressor p53 maintains genome stability and prevents malignant transformation by promoting cell cycle arrest and apoptosis. Both Mdm2 and Pirh2 have been shown to ubiquitylate p53 through their RING domains, thereby targeting p53 for prot
Autor:
Sunggeon Ko, Yung Joon Yoo, Dong Yeon Shin, Chaejoon Cheong, Cheryl H. Arrowsmith, Sung Min Song, Weontae Lee, Ji Hye Yun, Jung Gyu Lee, Yong-Keun Jung, Young Ho Jeon, George V. Avvakumov, Soo Hyun Eom, Sirano Dhe-Paganon, Yi Sheng, Gil Bu Kang
Publikováno v:
Journal of Biological Chemistry. 285:36070-36080
E2-25K/Hip2 is an unusual ubiquitin-conjugating enzyme that interacts with the frameshift mutant of ubiquitin B (UBB(+1)) and has been identified as a crucial factor regulating amyloid-β neurotoxicity. To study the structural basis of the neurotoxic
Autor:
Frederick Cheung, Ruslan Sanishvili, Jocelyne Lew, Vivian Saridakis, Andrzej Joachimiak, Dinesh Christendat, Micha Pennycooke, Jun Gu, Aled M. Edwards, Alexander F. Yakunin, Cheryl H. Arrowsmith, Ponni Anandakumar, Xiaohui Xu
Publikováno v:
Journal of Biological Chemistry. 279:23646-23653
ATP:cobalamin adenosyltransferase MMAB was recently identified as the gene responsible for a disorder of cobalamin metabolism in humans (cblB complementation group). The crystal structure of the MMAB sequence homologue from Thermoplasma acidophilum (
Autor:
Michael Proudfoot, Alexander F. Yakunin, Aled M. Edwards, Fred Cheung, Youngchang Kim, Micha Pennycooke, Ekaterina Kuznetsova, Xiaohui Xu, Cheryl H. Arrowsmith, Jun Gu, Dinesh Christendat, Andrzej Joachimiak
Publikováno v:
Journal of Biological Chemistry. 279:517-526
The protein TA0175 has a large number of sequence homologues, most of which are annotated as unknown and a few as belonging to the haloacid dehalogenase superfamily, but has no known biological function. Using a combination of amino acid sequence ana
Publikováno v:
Journal of Biological Chemistry. 278:47753-47761
USP7 or HAUSP is a ubiquitin-specific protease in human cells that regulates the turnover of p53 and is bound by at least two viral proteins, the ICP0 protein of herpes simplex type 1 and the EBNA1 protein of Epstein-Barr virus. We have overexpressed
Autor:
Ruslan Sanishvili, Roman A. Laskowski, Cheryl H. Arrowsmith, Tatiana Skarina, Janet M. Thornton, Elena Evdokimova, Gilles A. Lajoie, Alexei Savchenko, Andrzej Joachimiak, Aled M. Edwards, Alexander F. Yakunin, Amanda Doherty-Kirby
Publikováno v:
Journal of Biological Chemistry. 278:26039-26045
Structural proteomics projects are generating three-dimensional structures of novel, uncharacterized proteins at an increasing rate. However, structure alone is often insufficient to deduce the specific biochemical function of a protein. Here we dete
Autor:
Zhiru Yang, Liang Tong, Cheryl H. Arrowsmith, Aled M. Edwards, Alexander F. Yakunin, Alexei Savchenko, Rongguang Zhang
Publikováno v:
Journal of Biological Chemistry. 278:8804-8808
The open reading frame TM1643 of Thermotoga maritima belongs to a large family of proteins, with homologues in bacteria, archaea, and eukaryotes. TM1643 is found in an operon with two other genes that encode enzymes involved in the biosynthesis of NA