Zobrazeno 1 - 5
of 5
pro vyhledávání: '"11"'
Publikováno v:
Journal of Biological Chemistry. 283:10698-10706
Normal development of the immune system requires regulated processing of NF-kappaB2 p100 to p52, which activates NF-kappaB2 signaling. Constitutive production of p52 has been suggested as a major mechanism underlying lymphomagenesis induced by NF-kap
Autor:
Susan Cupo, John S. Mudgett, Nicole A. Chartrain, Karen Lowitz, Catherine E. Fitzgerald, Dennis M. Zaller, Ester Carballo-Jane, Stephen J. O'Keefe, Silvi Luell, Cordelia Rasa, Karen Owens, Shiow-Ling Chen, Denise M. Visco, Janey N. Parsons
Publikováno v:
Journal of Biological Chemistry. 282:34663-34671
The p38 MAP kinase signal transduction pathway is an important regulator of proinflammatory cytokine production and inflammation. Defining the roles of the various p38 family members, specifically p38alpha and p38beta, in these processes has been dif
Autor:
Seth L. Masters, Paul J. Baker
Publikováno v:
Journal of Biological Chemistry. 293:7068-7069
Inflammatory cell death, or pyroptosis, is triggered by pathogenic infections or events. It is executed by caspase-1 (in the canonical pyroptosis pathway) or caspase-11 (noncanonical pathway), each via production of a cell-lytic domain from the pyrop
Autor:
Marcin Poreba, Scott J. Snipas, Marcin Drag, Katarzyna Groborz, Guy S. Salvesen, Monica L. Gonzalez Ramirez
Publikováno v:
Journal of Biological Chemistry
Inflammatory cell death, or pyroptosis, is triggered by pathogenic infections or events. It is executed by caspase-1 (in the canonical pyroptosis pathway) or caspase-11 (noncanonical pathway), each via production of a cell-lytic domain from the pyrop
Autor:
Philippe J. Sansonetti, Muguette Jéhanno, Stephen E. Girardin, Dana J. Philpott, Dominique Mengin-Lecreulx, Pedro M. Alzari
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, 2005, 280 (46), pp.38648-38656. ⟨10.1074/jbc.M509537200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2005, 280 (46), pp.38648-38656. ⟨10.1074/jbc.M509537200⟩
Journal of Biological Chemistry, 2005, 280 (46), pp.38648-38656. ⟨10.1074/jbc.M509537200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2005, 280 (46), pp.38648-38656. ⟨10.1074/jbc.M509537200⟩
International audience; Nod1 is an intracellular pattern recognition molecule activated following bacterial infection, which senses a specific muropeptide (l-Ala-d-Glu-meso-DAP (diaminopimelic acid); "Tri(DAP)") from peptidoglycan. Here we investigat