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Autor:
M H Zhang, Svetlana Reilly, Jean-Luc Balligand, Raja Jayaram, Winifred Idigo, Yin Hua Zhang, Mark J. Crabtree, Ricardo Carnicer, Barbara Casadei
Publikováno v:
Journal of Biological Chemistry. 287:43665-43673
Myocardial constitutive No production depends on the activity of both endothelial and neuronal NOS (eNOS and nNOS, respectively). Stimulation of myocardial β(3)-adrenergic receptor (β(3)-AR) produces a negative inotropic effect that is dependent on
Autor:
Anuwat Dinudom, Sheerazed Boulkroun, David I. Cook, Il-Ha Lee, Christoph Korbmacher, Mark O. Wielpütz, Robert Rauh, Nicolette Farman
Publikováno v:
Journal of Biological Chemistry. 282:28264-28273
Regulation of the epithelial sodium channel (ENaC) is highly complex and may involve several aldosterone-induced regulatory proteins. The N-Myc downstream-regulated gene 2 (NDRG2) has been identified as an early aldosterone-induced gene. Therefore, w
Autor:
Mark D. Parker, Christopher M. Daly, Jing Lu, Walter F. Boron, Peter M. Piermarini, Marc F. Pelletier, Harindarpal S. Gill
Publikováno v:
Journal of Biological Chemistry. 281:19241-19250
Others report that carbonic anhydrase II (CA II) binds to the C termini of the anion exchanger AE1 and the electrogenic Na/HCO3 cotransporter NBCe1-A, enhancing transport. After injecting oocytes with NBCe1-A cRNA (Day 0), we measured NBC current (I(
Publikováno v:
Journal of Biological Chemistry. 279:12529-12534
The amiloride-sensitive epithelial Na(+) channel (ENaC) controls Na(+) transport into cells and across epithelia. So far, four homologous subunits of mammalian ENaC have been isolated and are denoted as alpha, beta, gamma, and delta. ENaCdelta can as
Publikováno v:
Journal of Biological Chemistry. 279:12503-12510
L-type dihydropyridine-sensitive voltage dependent Ca(2+) channels (L-VDCCs; alpha(1C)) are crucial in cardiovascular physiology. Currents via L-VDCCs are enhanced by hormones and transmitters operating via G(q), such as angiotensin II (AngII) and ac
Publikováno v:
Journal of Biological Chemistry. 278:9552-9559
Progesterone has long been considered the primary mediator of Xenopus oocyte maturation. We have recently shown, however, that androgens, which are equal or more potent promoters of maturation and are present at higher levels in ovulating frogs, may
Autor:
Rolf Gräbner, Ernst Malle, Regine Heller, Gunther Marsche, Alexander Nuszkowski, Anett Unbehaun
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
Hypochlorous acid/hypochlorite, generated by the myeloperoxidase/H(2)O(2)/halide system of activated phagocytes, has been shown to oxidize/modify low density lipoprotein (LDL) in vitro and may be involved in the formation of atherogenic lipoproteins
Autor:
Thomas Michel, Margaret Arstall, Ralph A. Kelly, Douglas J. Opel, Chantal Dessy, Olivier Feron
Publikováno v:
Journal of Biological Chemistry. 273:30249-30254
The endothelial isoform of nitric oxide synthase (eNOS) is dually acylated and thereby targeted to signal-transducing microdomains termed caveolae. In endothelial cells, eNOS interacts with caveolin-1, which represses eNOS enzyme activity. In cardiac
Autor:
Phillipe Bulet, Martine Verger-Bocquet, Michel Salzet, Jean Malecha, Wolfgang Clauss, Wolf-Michael Weber
Publikováno v:
Journal of Biological Chemistry. 271:7237-7243
Purification of a material immunoreactive to an antiserum against the C-terminal part of the oxytocin (Pro-Leu-Gly-amide) and present in the central nervous system of the Pharyngobdellid leech Erpobdella octoculata was performed by reversed-phase hig
Publikováno v:
Journal of Biological Chemistry. 271:6398-6402
The G-protein-gated inward-rectifying K+ channel GIRK1 has been demonstrated in heart and brain. These tissues also both express the M2, M3, and M4, muscarinic acetylcholine receptors (mAChR) (Gadbut, A.P., and Galper, J.B. (1994),J. Biol. Chem. 269,