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Autor:
James Wickens, Adam P. Hardy, Anthony Tumber, Martine I. Abboud, Michael A. McDonough, Christopher T. Lohans, Rasheduzzaman Chowdhury, Christopher M. West, Kerstin Lippl, Christopher J. Schofield, Elisabete Pires, Tongri Liu
Publikováno v:
The Journal of Biological Chemistry
In animals, the response to chronic hypoxia is mediated by prolyl hydroxylases (PHDs) that regulate the levels of hypoxia-inducible transcription factor α (HIFα). PHD homologues exist in other types of eukaryotes and prokaryotes where they act on n
Publikováno v:
The Journal of Biological Chemistry
Investigations of bacterial resistance strategies can aid in the development of new antimicrobial drugs as a countermeasure to the increasing worldwide prevalence of bacterial antibiotic resistance. One such strategy involves the TipA class of transc
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
J Biol Chem
Universidade de São Paulo (USP)
instacron:USP
J Biol Chem
The RNA exosome is a multisubunit protein complex involved in RNA surveillance of all classes of RNA, and is essential for pre-rRNA processing. The exosome is conserved throughout evolution, present in archaea and eukaryotes from yeast to humans, whe
Autor:
Jun-ichi Kurita, Noriyoshi Isozumi, Ru Zhang, Suthitar Singkaravanit-Ogawa, Yoshitaka Takano, Shinya Ohki, Masashi Mori, Pamela Gan, Ken Shirasu, Tomohiro Imamura, Ryuta Okuta
Publikováno v:
The Journal of Biological Chemistry
Fungal plant pathogens secrete virulence-related proteins, called effectors, to establish host infection; however, the details are not fully understood yet. Functional screening of effector candidates using Agrobacterium-mediated transient expression
Autor:
Viren V. Patel, Victoria A. Higman, Catherine R. Back, Angela H. Nobbs, Howard F. Jenkinson, Daniel Frankel, Steven G. Burston, Alice E. Parnell, Paul R. Race, Kristian Le Vay, Matthew P. Crump
Publikováno v:
Back, C, Higman, V A, Le Vay, K, Patel, V V, Parnell, A E, Frankel, D, Jenkinson, H F, Burston, S G, Crump, M P, Nobbs, A H & Race, P R 2020, ' The streptococcal multidomain fibrillar adhesin CshA has an elongated polymeric architecture ', Journal of Biological Chemistry . https://doi.org/10.1074/jbc.RA119.011719
J Biol Chem
J Biol Chem
The cell surfaces of many bacteria carry filamentous polypeptides termed adhesins that enable binding to both biotic and abiotic surfaces. Surface adherence is facilitated by the exquisite selectivity of the adhesins for their cognate ligands or rece
Autor:
Tinatin I. Brelidze, Ze-Jun Wang, Stephanie M. Soohoo, Grzegorz Piszczek, Purushottam B. Tiwari
Publikováno v:
J Biol Chem
Ether-a-go-go (EAG) potassium selective channels are major regulators of neuronal excitability and cancer progression. EAG channels contain a Per–Arnt–Sim (PAS) domain in their intracellular N-terminal region. The PAS domain is structurally simil
Publikováno v:
J Biol Chem
The natural resistance-associated macrophage protein (Nramp) family encompasses transition metal and proton cotransporters that are present in many organisms from bacteria to humans. Recent structures of Deinococcus radiodurans Nramp (DraNramp) in mu
Autor:
Jingxia Shao, Yafei Qi, Pei Lei, Liru Yan, Xiayan Liu, Xiaomin Wang, Jingjing Meng, Lijun An, Jun Zhao, Huimin Li, Fei Yu
Publikováno v:
J Biol Chem
Chloroplast development and photosynthesis require the proper assembly and turnover of photosynthetic protein complexes. Chloroplasts harbor a repertoire of proteases to facilitate proteostasis and development. We have previously used an Arabidopsis
Autor:
Donald F. Hunt, Juan Ausió, Takashi Ueda, Dina L. Bai, Manjinder S. Cheema, Jeffrey Shabanowitz, Ciro Rivera-Casas, José M. Eirín-López, Robert Anthony D’Ippolito, Naoki Minamino, Harold E. Kasinsky
Publikováno v:
J Biol Chem
Protamines are small, highly-specialized, arginine-rich, and intrinsically-disordered chromosomal proteins that replace histones during spermiogenesis in many organisms. Previous evidence supports the notion that, in the animal kingdom, these protein
Publikováno v:
J Biol Chem
Virulent strains of the bacterial pathogen Vibrio cholerae cause the diarrheal disease cholera by releasing cholera toxin into the small intestine. V. cholerae acquired its cholera toxin genes by lysogenic infection with the filamentous bacteriophage