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Autor:
Hong Zhao, Leiliang Zhang, Guoyang Wu, Shaoyong Li, Kattareeya Kumthip, Ethan M. Weinberg, Wen-Chi Chen, Mark A. Brockman, Wenyu Lin, Nikolaus Jilg, Lee F. Peng, Jorge Méndez-Navarro, Detlef Schuppan, Kaku Goto, Raymond T. Chung
Publikováno v:
The Journal of Biological Chemistry
HIV/HCV coinfection leads to accelerated hepatic fibrosis progression, with higher rates of cirrhosis, liver failure, and liver death than does HCV mono-infection. However, the profibrogenic role of HIV on hepatocytes and hepatic stellate cells (HSC)