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Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:1413-1416
Background Ivermectin is an antiparasitic drug being investigated in clinical trials for the prevention of COVID-19. However, there are concerns about the quality of some of these trials. Objectives To conduct a meta-analysis with randomized controll
Autor:
Atefeh Bonyadi, Fariborz Mansour-Ghanaei, Farhang Babamahmoodi, Esmat Radmanesh, Hadiseh Hosamirudsari, Javad Khodadadi, Sara Sayar, Zeinab Mehrabi, Amir Reza Bahadori, Shahin Merat, Minoo Moghimi, Gholamali Eslami, Hashem Mousavi, Lotfollah Davoodi, Mona Ebrahimzadeh, Farahnaz Joukar, Amir Anushiravani, Ali Ali Asgari, Ali Reza Davoudi Badabi, Elham Barahimi, Saeed Jelvay, Zahra Poormontaseri, Aida Zeinali, Nasim Khajavirad, Minoosh Shabani, Hamideh Abbaspour Kasgari, Zohreh Azarkar, Rohollah Moslemi, Ahmad Hormati, Azadeh Ebrahimzadeh, Hani Esmaeilian, Shokrollah Salmanzadeh, Elham Akbarpour, Lili Rezaie Keikhaie, Kaitlyn McCann, Amir Mohammad Shabani, Abdolali Tousi, Mohammad Abdollahi, Sara Mobarak, Mohammadreza Naghipour, Hadi Mirzaei, Mohammadreza Salehi, Shervin Shokouhi, Bryony Simmons, Morteza Mobarak, Helia Nateghi Baygi, Jacob Levi, Mehdi Hassaniazad, Andrew Hill, Zahra Arizavi, Nasrollah Hasooni Bahrini, Seyed Ali Dehghan Manshadi, Fatemeh Dehghani, Hannah Wentzel, Hossein Pourmasoomi, Masoome Noori Jangi, Shoeleh Yaghoubi, Alireza Nateghi Baygi, Mehdi Salasi, Farnaz Zolfaghari, Sara Yeganeh, Elmira Azimi, Jalal Karimi, Hafez Fakheri, Mahdi Afshari, Tofigh Yaghubi Kalurazi, Anahita Sadeghi, Farshid Abedi, Sajedeh Mousaviasl, Zahra Nekoukar, Dorsa Merat, Masood Ziaee
Publikováno v:
Journal of Antimicrobial Chemotherapy
Background: The combination of sofosbuvir (SOF) and daclatasvir (DCV) has shown preliminary efficacy for patients with COVID-19 in five open-label studies with small sample sizes. This larger trial aimed to assess if the addition of sofosbuvir and da
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:338-344
Background CoNS bacteraemia causes significant neonatal morbidity. Previous work has suggested that β-lactam antibiotics vary in their binding affinity to PBP2a (produced by the mecA gene) present in most CoNS. Objectives We evaluated cefazolin MICs
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:425-432
Objectives Bacterial antibiotic tolerance is responsible for the recalcitrance of chronic infections. This study aims to investigate a potential drug that can effectively kill antibiotic-tolerant bacteria and evaluate the ability of this drug on the
Publikováno v:
J Antimicrob Chemother
ObjectivesComplicated urinary tract infections (cUTIs) are frequently encountered in hospitals and ICUs. Increasingly, the causative pathogens harbour enzymatic resistance mechanisms. Taniborbactam is a novel β-lactamase inhibitor with activity agai
Autor:
Tristan Delory, Elisabeth Bouvet, Florence Tubach, Nathan Peiffer-Smadja, P. Jeanmougin, Sylvie Lariven, Josselin Le Bel, F.-X. Lescure, Pierre-Yves Boëlle
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:524-530
Background Hospital-based surveillance of antimicrobial resistance may be irrelevant as a guide to antimicrobial use for urinary tract infections (UTIs) in primary care. Objectives To highlight the value of online computerized decision support system
Autor:
Gilles Peytavin, Florence Damond, Sophie Matheron, A. Bachelard, Samuel Lebourgeois, Gilles Collin, Charlotte Charpentier, Jade Ghosn, Quentin Le Hingrat, Diane Descamps, Valentine Marie Ferré
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:409-412
Background HIV-2 resistance to integrase strand-transfer inhibitors (INSTIs) is characterized by two main pathways: (i) mutations at codons 143, 148 and155; and (ii) amino acid insertion after integrase codon 231 (231ins). Objectives To complete INST
Autor:
Ravindra K. Gupta, Judith Breuer, Sunando Roy, Caroline A. Sabin, Obinna Ogbanufe, Man Charurat, Rawlings Datir, Fati Murtala-Ibrahim, Patrick Dakum, Vivian Kwaghe, Nicaise Ndembi, Kate El Bouzidi, Dan Frampton
Publikováno v:
Journal of Antimicrobial Chemotherapy
Background Deep sequencing could improve understanding of HIV treatment failure and viral population dynamics. However, this tool is often inaccessible in low- and middle-income countries. Objectives To determine the genetic patterns of resistance em
Autor:
D J van Vessem, Caspar J. Hodiamont, S E Berends, R. M. Van Hest, N Hakkens, M D de Jong, Ron A. A. Mathôt, Nicole P. Juffermans
Publikováno v:
Journal of antimicrobial chemotherapy, 76(11), 2941-2949. Oxford University Press
Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy
Background The advocated pharmacokinetic/pharmacodynamic (PK/PD) target for vancomycin, AUC/MIC ≥ 400 mg·h/L, may not be reached with a conventional fixed starting dose of 1000 mg in critically ill patients, but increasing the dose may cause nephr
Autor:
Valeska Laisnez, Wesley Mattheus, An Van den Bossche, Naïma Hammami, Margo Maex, Dieter Van Cauteren, Pieter-Jan Ceyssens, Natalie Fischer
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives Shigella sonnei resistant to first-line antibiotics azithromycin and ciprofloxacin are on the rise globally. The aim of this study was to describe the epidemiology of MDR S. sonnei in Belgium and to identify origins and circulating cluster