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Autor:
Henry Saedi-Kwon, Jacqueline Schwartz, D Erin Wilson, Eric Chang, Dominic Chan, Regina Won, R. Brigg Turner
Publikováno v:
Journal of Antimicrobial Chemotherapy. 73:772-778
Ceftaroline is often used in durations greater than that studied in clinical trials. Several retrospective, non-comparative studies have suggested a higher than anticipated incidence of neutropenia in patients receiving prolonged treatment with cefta
Autor:
Kristen R. Poncsak, Sheryl A. Zelenitsky, J. Christine Davis, Lavern M. Vercaigne, Robert E. Ariano
Publikováno v:
Journal of Antimicrobial Chemotherapy. 72:1802-1811
Objectives To evaluate the ability of body-weight-driven renal function assessment (RFA) formulae to predict on-target elimination rate ranges for gentamicin in patients with varying degrees of renal function. Methods A 6 year retrospective pharmacok
Publikováno v:
Journal of Antimicrobial Chemotherapy. 70:3100-3106
BACKGROUND Anidulafungin does not undergo hepatic metabolism like the other echinocandins. Therefore, there is a perception that anidulafungin may be less hepatotoxic or less likely to exacerbate existing liver damage. This has not been substantiated
Autor:
Kyung Soo Lee, Hong Kwan Kim, Nam Yong Lee, Hye Yun Park, Jhingook Kim, Byeong-Ho Jeong, Kyeongman Jeon, O Jung Kwon, Won-Jung Koh, Yong Soo Choi, Hee Jae Huh
Publikováno v:
Journal of Antimicrobial Chemotherapy. 70:3127-3133
OBJECTIVES Fluoroquinolones (FQs) are the most important second-line drugs for MDR-TB treatment. Therapeutic options for FQ-resistant (FQ-R) MDR/XDR-TB are very limited. The purpose of the present study was to determine treatment outcomes and risk fa
Autor:
Dimitrios Farmakiotis, Emily Wang, Deborah McCue, Hagop M. Kantarjian, Dimitrios P. Kontoyiannis, Daisy Yang, Michael S. Mathisen
Publikováno v:
Journal of Antimicrobial Chemotherapy. 70:2362-2368
Objectives The epidemiology and clinical course of candidaemia in patients with acute leukaemia, a population frequently exposed to antifungals, have not been extensively studied. In the present contemporary series of acute leukaemia patients, we des
Autor:
Nitipong Permpalung, Leonel Mendoza, Ariya Chindamporn, Navaporn Worasilchai, Anawin Sanguankeo, Rongpong Plongla, Leilani Paitoonpong, Sikarin Upala
Publikováno v:
Journal of Antimicrobial Chemotherapy. 70:1885-1892
Objectives Human pythiosis is a life-threatening disease for which no standard treatment protocols with proven efficacy exist. We present the results of our institutional pythiosis treatment protocol, composed of surgery, antifungal agents, iron chel
Autor:
Jette Nygaard Jensen, Nis Nørgaard, Magnus Arpi, Jonas Bredtoft Boel, Rasmus Bisbjerg, Jens Otto Jarløv, Valeria Antsupova
Publikováno v:
Journal of Antimicrobial Chemotherapy. 69:3372-3378
Background Fluoroquinolones are extensively used as prophylaxis for transrectal ultrasound-guided biopsy of the prostate (TRUBP). Emerging fluoroquinolone resistance and selection of multiresistant organisms warrant new prophylactic strategies. Pivme
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives In British Columbia (BC), Canada, neuraminidase inhibitors (NIs) were publicly funded during the 2009 A(H1N1)pdm09 pandemic for treatment of high-risk patients and/or anyone with moderate-to-severe illness. We assessed antiviral effectiven
Autor:
Mark Booth, Adetayo Kasim, Maame Anima Sarfo, Fred S. Sarfo, David Chadwick, Richard Phillips
Publikováno v:
Journal of Antimicrobial Chemotherapy. 69:254-261
OBJECTIVES Information on the long-term effectiveness and tolerability of efavirenz- or nevirapine-based antiretroviral therapy (ART) in Africa is lacking. The primary objective of this retrospective observational study was to compare the long-term c
Autor:
Chien-Yuan Chen, Wen-Chien Chou, Ming Yao, Jih-Luh Tang, Bo-Sheng Ko, Shang-Yi Huang, Po-Ren Hsueh, Hwei-Fang Tien, Woei Tsay
Publikováno v:
Journal of Antimicrobial Chemotherapy. 68:2632-2635
This study was intended to analyse the clinical characteristics and outcomes of patients with infections due to Candida guilliermondii complex and evaluate in vitro susceptibilities of the isolates.We searched the Mycology Database of the National Ta