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Autor:
Peninah Menza, Robert Kimutai, Anke E. Kip, Fabiana Alves, Monique Wasunna, Ermias Diro, Bewketu Mengesha, Asrat Hailu, Jos H. Beijnen, Thomas P. C. Dorlo, Séverine Blesson
Publikováno v:
Journal of Antimicrobial Chemotherapy
Background Despite high HIV co-infection prevalence in Ethiopian visceral leishmaniasis (VL) patients, the adequacy of antileishmanial drug exposure in this population and effect of HIV-VL co-morbidity on pharmacokinetics of antileishmanial and antir
Autor:
Ariya Chindamporn, Saowaluck Yasri, Thira Sirisanthana, Romanee Chaiwarith, Tim R. Cressey, Navaporn Worasilchai, Quanhathai Kaewpoowat
Publikováno v:
Journal of Antimicrobial Chemotherapy. 76:1041-1045
ObjectivesTo assess the pharmacokinetic of itraconazole capsule formulation and its active metabolite, hydroxyitraconazole, in adults with HIV diagnosed with talaromycosis in an endemic area, and to evaluate the drug–drug interaction between itraco
Effect of high-dose rifampicin on efavirenz pharmacokinetics: drug–drug interaction randomized trial
Autor:
Daniel, Atwine, Elisabeth, Baudin, Thibaut, Gelé, Winnie, Muyindike, Kenneth, Mworozi, Racheal, Kyohairwe, Keneth, Kananura, Patrick, Orikiriza, Dan, Nyehangane, Deborah, K T Nanjebe, Valérie, Furlan, Céline, Verstuyft, Aurélie, Barrail-Tran, Anne-Marie, Taburet, Maryline, Bonnet, P, Justumus
Publikováno v:
Journal of Antimicrobial Chemotherapy. 75:1250-1258
We regret that this article is behind a paywall.
Background: High-dose rifampicin is considered to shorten anti-TB treatment duration but its effect on antiretroviral metabolism is unknown. Objectives: To assess the effect of doubling the rifamp
Background: High-dose rifampicin is considered to shorten anti-TB treatment duration but its effect on antiretroviral metabolism is unknown. Objectives: To assess the effect of doubling the rifamp
Autor:
Javier García-Abellán, Vanesa Agulló, Marta Fernández-González, Félix Gutiérrez, Sergio Padilla, Mar Masiá, José A. García
Publikováno v:
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
BackgroundThe time at which the protective effect of starting ART is achieved in male rectal and genital reservoirs is not clearly established.ObjectivesTo quantify HIV-1 RNA decay towards virological suppression in rectal mucosa and semen in MSM sta
Autor:
Massimiliano Donzelli, Emili Letang, Manuel Haschke, Stefan Gaugler, Manuel Battegay, Benjamin Berger, Stephan Krähenbühl, Urs Duthaler, Alex Natamatungiro, Dorcas Mnzava, Stefan Erb
Publikováno v:
Journal of Antimicrobial Chemotherapy. 73:2729-2737
Objectives We evaluated whether dried blood spots (DBS) are suitable to monitor combined ART when samples are collected in rural Tanzania and transported over a long distance to a specialized bioanalytical laboratory. Methods Plasma and DBS samples w
Autor:
X Salgado, Covadonga Torres, Antonio Ocampo, Evelyn Martinez, M. Rodriguez, Pere Domingo, Miguel Yzusqui, J Diz, Daniel Podzamczer, A. Muñoz, M A Sepúlveda, A Bahamonde, J F Lorenzo, A Casado, Nerea Rozas, José E. P. Santos, M I Mayorga, J R Barberá, Pablo Bachiller, P. Fernandez
Publikováno v:
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Objectives: To analyse lipid changes and tolerability in a cohort of HIV-infected patients who switched their anti- retroviral regimens to rilpivirine/emtricitabine/tenofovir (RPV/FTC/TDF) in a real-world setting. Methods: PRO-STR is a 48 week prospe
Autor:
Angela Colbers, David M. Burger, Pauline D.J. Bollen, Veroniek E M Harbers, Marjolijn Duisenberg-van Essenberg, Marieke Roskam-Kwint
Publikováno v:
Journal of Antimicrobial Chemotherapy, 73, 2430-2434
Journal of Antimicrobial Chemotherapy, 73, 9, pp. 2430-2434
Journal of Antimicrobial Chemotherapy, 73, 9, pp. 2430-2434
Background If HIV patients are unconscious or cannot swallow tablets for other reasons, antiretroviral medication is crushed and dissolved prior to administration. Crushing can alter drug exposure, possibly leading to treatment failure, development o
Autor:
Fernando Agüero, Asunción Moreno, Miró Jm, Christian Manzardo, Juan Ambrosioni, Pablo Ruiz, Montserrat Laguno, Alejandro Forner, Anna Lligoña, María-Carlota Londoño, Antoni Rimola, Josep Costa
Publikováno v:
Journal of Antimicrobial Chemotherapy. 71:3195-3201
OBJECTIVES IFN-based therapy against hepatitis C recurrence after liver transplantation (LT) has poor effectiveness and tolerability. In HIV/HCV-coinfected liver transplant recipients, the results are even poorer. Here, we report our experience using
Autor:
Emma L. Best, Dale N. Gerding, Oliver A. Cornely, Carl Erik Nord, Hilke Kracker, H. H. Locher, George H. Talbot, Pascal Charef, S. Sambol, Mark H. Wilcox, David W. Hecht, J. R. Osmolski, Thomas J. Louie, Martha Buitrago
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives: The aim of this study was to evaluate the susceptibilities of Clostridium difficile isolates to cadazolid, a novel antibiotic for the treatment of C. difficile infection. Methods: Ribotyping and susceptibilities were determined for C. dif
Publikováno v:
Journal of Antimicrobial Chemotherapy. 70:3100-3106
BACKGROUND Anidulafungin does not undergo hepatic metabolism like the other echinocandins. Therefore, there is a perception that anidulafungin may be less hepatotoxic or less likely to exacerbate existing liver damage. This has not been substantiated