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Publikováno v:
Journal of Alzheimer's disease : JAD. 78(2)
Background: Alzheimer’s disease (AD), the prevalent dementia in the elderly, involves many related and interdependent pathologies that manifest simultaneously, leading to cognitive impairment and death. Amyloid-β (Aβ) accumulation in the brain tr
Publikováno v:
Journal of Alzheimer's disease : JAD. 50(1)
Alzheimer’s disease (AD), the prevalent dementia in the elderly, involves many related and interdependent pathologies that manifests simultaneously, eventually leading to cognitive impairment and death. No treatment is currently available; however,
Autor:
Beka Solomon
Publikováno v:
Journal of Alzheimer's disease : JAD. 9
Site-directed antibodies which modulate conformation of amyloid-beta peptide (Abeta) became the theoretical basis of the immunological approach for treatment of Alzheimer's disease (AD). Indeed, antibodies towards the EFRH sequence, located between a