Zobrazeno 1 - 10
of 137
pro vyhledávání: ''
Autor:
Amy D. Klion, Florence Roufosse, Marc E. Rothenberg, Suyong Yun Kirby, Jane H Bentley, Jonathan Steinfeld, Martyn J. Gilson, Eric S. Bradford, Steven W. Yancey, Andrew J. Wardlaw, Jean-Emmanuel Kahn, Gerald J. Gleich
Publikováno v:
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, Elsevier, 2020, 146 (6), pp.1397-1405. ⟨10.1016/j.jaci.2020.08.037⟩
Journal of allergy and clinical immunology
Journal of Allergy and Clinical Immunology, Elsevier, 2020, 146 (6), pp.1397-1405. ⟨10.1016/j.jaci.2020.08.037⟩
Journal of allergy and clinical immunology
Background: Anti–IL-5 therapy is a potential treatment for patients with hypereosinophilic syndrome (HES), although its clinical efficacy is unclear. Objective: We sought to investigate the clinical efficacy and safety of mepolizumab versus placebo
Autor:
Theodore A. Omachi, L. Islam, Claus Bachert, Rui Zhu, Philippe Gevaert, Jonathan Corren, Monica Ligueros-Saylan, Joseph K. Han, Joaquim Mullol, Kit Wong, Ryan Owen, Derrick Kaufman, Monet Howard, Stella E. Lee
Publikováno v:
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by IgE hyperproduction and eosinophilic inflammation. The anti-IgE antibody, omalizumab, has demonstrated efficacy in patients with CRSwNP and comorbid asthma previously.
Autor:
Joaquim Mullol, Joseph K. Han, Rui Zhao, Kit Wong, Randall A. Ow, Monet Howard, L. Islam, Claus Bachert, Monica Ligueros-Saylan, Theodore A. Omachi, Stella E. Lee, Jonathan Corren, R. Saenz, Philippe Gevaert
Publikováno v:
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) frequently remains uncontrolled despite maximal medical therapy and sinonasal surgery, presenting several unmet needs and challenges. Omalizumab previously demonstrated efficacy in CRSwNP
Autor:
Jianping Zhao, Jing Liu, Fankai Meng, Gaoxiang Wang, Liang Zou, Tiebin Jiang, Jungang Xie, Xiaoxi Zhou, Yang Cao, Jia Wei, Liting Chen, Na Wang, Wei Wang, Jianfeng Zhou, Zekai Mao, Hui Cheng, Gang Huang, Liang Huang, Hui Luo, Xing Chen, Lifang Huang
Publikováno v:
Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology
Background Accumulating evidence proposed JAK inhibitors as therapeutic targets warranting rapid investigation. Objective This study evaluated the efficacy and safety of ruxolitinib, a Janus-associated kinase (JAK1/2) inhibitor, for COVID-19. Methods
Timing and duration of omalizumab response in patients with chronic idiopathic/spontaneous urticaria
Autor:
Sam Khalil, Jonathan A. Bernstein, Karin Rosén, Marta Ferrer, Karina Raimundo, Benjamin Trzaskoma, Theodore A. Omachi, Evgeniya Antonova, James L. Zazzali, Allen P. Kaplan
Publikováno v:
Journal of Allergy and Clinical Immunology. 137(2):474-481
Background Few data are available that describe response patterns in patients with chronic idiopathic urticaria (CIU)/chronic spontaneous urticaria (CSU) treated with omalizumab. Objective We sought to describe response patterns by using data from th
Publikováno v:
Journal of Allergy and Clinical Immunology. 145:AB235
Autor:
Hubert Chen, Mark D. Eisner, Mary S. Bradley, Carlos Iribarren, Kenneth J. Rothman, Gillis Carrigan
Publikováno v:
Journal of Allergy and Clinical Immunology.
Autor:
Alexander A. Navarini, Tatjana Petkvic, Urs C. Steiner, Joerg Sebach, Arthur Helbling, Nicole Graf, Meike Distler, Carla Murer, Peter Schmid-Grendelmeier, Peter Jandus, Lars E. French, Tatjana Maul
Publikováno v:
Journal of Allergy and Clinical Immunology. 143:AB134
Publikováno v:
Journal of Allergy and Clinical Immunology. 143:AB97
Autor:
David Elkayam, Ramy A. Mahmoud, Per Gisle Djupesland, John C. Messina, Colette Kosik-Gonzalez, Donald A. Leopold
Publikováno v:
Journal of Allergy and Clinical Immunology. 143:126-134.e5
Background Chronic rhinosinusitis is common and sometimes complicated by nasal polyps (NPs). Corticosteroid nasal sprays are often unsatisfactory because they are ineffective at delivering medication to high/deep sites of inflammation. Objective We s