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Autor:
Amber N. Pepper, Dennis K. Ledford
Publikováno v:
Journal of Allergy and Clinical Immunology. 141:1570-1577
Nasal and ocular challenges facilitate the evaluation of subjective and objective responses to defined allergen or irritant exposure. Nasal and ocular allergen challenges are the gold standard to diagnose allergic rhinitis and conjunctivitis, respect
Autor:
Stephen Pawsey, Charles W. Frankish, Roderick Peter Hafner, Kristen Armstrong, Mark W. Tenn, Anne K. Ellis, Lisa M. Steacy
Publikováno v:
Journal of Allergy and Clinical Immunology. 145:610-618.e9
Grass allergen peptides are in development for the treatment of grass pollen-induced allergic rhinoconjunctivitis. A previous randomized, placebo-controlled study demonstrated that grass allergen peptides significantly improved total rhinoconjunctivi
Autor:
Siegfried Jäger, Michel Melac, Margitta Worm, Hans-Jørgen Malling, Alain Didier, A. Montagut, C. Andre, Friedrich Horak, Olivier de Beaumont
Publikováno v:
Journal of Allergy and Clinical Immunology. 120:1338-1345
Background Sublingual immunotherapy is well tolerated and data suggest its effectiveness for the treatment of allergic rhinitis in adults, but it lacks optimum dose definition. Objective To assess the efficacy, safety, and optimal dose of grass polle
Publikováno v:
Journal of Allergy and Clinical Immunology. 111:807-812
Background: Incident sensitization to common allergens in the setting of sensitization to an occupational allergen has not been described. Objective: Our aim was to determine the risk and timing of development of sensitization to common allergens in
Publikováno v:
Journal of Allergy and Clinical Immunology. 109:777-783
Background: Birch pollen is a common allergen in northern, central, and eastern Europe. Earlier studies of specific immunotherapy using birch pollen extract were not placebo-controlled or were only preseasonal. Long-term, placebo-controlled studies w
Autor:
Sue Boonlayangoor, Usama Gabr, Robert M. Naclerio, Fuad M. Baroody, Lauran Haney, Christopher Blair, Kenneth Thompson, Mark Nelson
Publikováno v:
Journal of Allergy and Clinical Immunology. 108:424-429
Background: Although it is not proven, one factor considered important in the development of sinusitis is allergic rhinitis. Objective: The purpose of this study was to determine whether ongoing allergic rhinitis enhances the infection and inflammati
Autor:
Javier Subiza, J A Jiménez, Sebastián Varela, B García, R Panzani, José Luis Subiza, M. Jerez, Rosa Rodriguez
Publikováno v:
Journal of Allergy and Clinical Immunology. 100:748-754
Objective: The existence of Platanus pollinosis is not generally accepted despite the production of very large quantities of airborne Platanus pollen in many cities of the United States and Europe. The aim of this study was to investigate if Platanus
Autor:
Zenner, HP, Baumgarten, C, Rasp, G, Fuchs, T, Kunkel, G, Hauswald, B, Ring, J, Effendy, Isaak, Behrendt, W, Frosch, PJ, Przybilla, B, Brunner, FX, Merk, HF, Kapp, A, Schnitker, J, Wolf, H
Publikováno v:
Journal of Allergy and Clinical Immunology. 100:23-29
Background: Short-term immunotherapy (STI) can be beneficial for patients who are noncompliant,vith long-term specific immunotherapy. Objective: The efficacy and tolerance of STI with seven pre-seasonal injections of molecular standardized allergens
Autor:
Anna Maria Riccio, C Bertolini, Marcello Bagnasco, Tiziana Truffeli, Giorgio Walter Canonica, Giovanni Passalacqua, Giorgio Ciprandi, Nicola Fiorino, V. Ricca
Publikováno v:
Journal of Allergy and Clinical Immunology. 99:301-307
Azelastine is a topical antihistamine, clinically demonstrated to be effective in allergic rhinitis.We evaluated the clinical efficacy and the antiallergic activity of azelastine nasal spray, administered 0.56 mg per day, 0.28 mg per day, or on deman
Autor:
Errol P. Prens, Alex KleinJan, E. C. M. Hoefsmit, Adriaan Holm, Tom Godthelp, Peter Doornenbal, E. Rijntjes, Paul G.H. Mulder, W. J. Fokkens
Publikováno v:
Journal of Allergy and Clinical Immunology. 97:800-811
Background: Eosinophils are thought to play an important role in the symptomatology and pathophysiology of allergic rhinitis. Most quantitative studies on eosinophils in nasal mucosa have focused on the dynamics of eosinophils in the acute and late p