Zobrazeno 1 - 10
of 63
pro vyhledávání: ''
Autor:
Sally E. Wenzel, David T. Mauger, George R. Washko, Eric A. Hoffman, Leonard B. Bacharier, Mary Clare McGregor, Samuel Peterson, Daphne Lew, Joshua Brownell, J.S. Boomer, Maanasi Samant, Ajay Sheshadri, John V. Fahy, K. Schechtman, Chase S. Hall, Loren C. Denlinger, Elliot Israel, Charles W. Goss, Stephen McEleney, Sean B. Fain, James G. Krings, Mario Castro
Publikováno v:
Journal of Allergy and Clinical Immunology. 148:752-762
Currently, there is limited knowledge regarding which imaging assessments of asthma are associated with accelerated longitudinal decline in lung function.We aimed to assess whether quantitative computed tomography (qCT) metrics are associated with lo
Autor:
Richardae Araojo, Celeste Eng, Esteban G. Burchard, Ronald L. Rabin, P.F. Huang, Jose R. Rodriguez-Santana, Jonathan Witonsky, Maria G. Contreras, Donglei Hu, Eric M. Wohlford, Christine Merenda, Jennifer R. Elhawary, Scott Huntsman, Cecile T.J. Holweg, Sam S. Oh, Michael A. LeNoir, Luisa N. Borrell, L. Millette, Angel C.Y. Mak, Christine M. Lee
Publikováno v:
The Journal of allergy and clinical immunology, vol 148, iss 5
J Allergy Clin Immunol
J Allergy Clin Immunol
BACKGROUND: Asthma is a heterogeneous disease. Clinical blood parameters differ by race/ethnicity and are used to distinguish asthma subtypes and inform therapies. Differences in subtypes may explain population-specific trends in asthma outcomes. How
Autor:
Cullen M. Dutmer, Andrea J. Apter, Daniel A. Searing, William C. Anderson, Stanley J. Szefler
Publikováno v:
Journal of Allergy and Clinical Immunology. 140:671-680
In this year's Advances in Asthma review, we discuss viral infections in asthmatic patients and potential therapeutic agents, the microbiome, novel genetic associations with asthma, air quality and climate effects on asthma, exposures during developm
Autor:
Jessica Lasky-Su, Su H. Chu, Vincent J. Carey, Scott T. Weiss, Augusto A. Litonjua, Rachel S. Kelly, Nancy Laranjo, Hanna M. Knihtilä, George T. O'Connor, Robert S. Zeiger, Leonard B. Bacharier, Benjamin J. Stubbs
Publikováno v:
J Allergy Clin Immunol
BACKGROUND: Lung function impairment in early life often persists into adulthood. Therefore, identifying risk factors for low childhood lung function is crucial. OBJECTIVE: We examined the effect of 25-hydroxyvitamin D (25[OH]D) level and childhood a
Autor:
Eric A. Hoffman, Jason C. Woods, Abhaya Trivedi, Mario Castro, David S. Gierada, Chase S. Hall
Publikováno v:
Journal of Allergy and Clinical Immunology. 139:1-10
There have been significant advancements in the various imaging techniques being used for the evaluation of asthmatic patients, both from a clinical and research perspective. Imaging characteristics can be used to identify specific asthmatic phenotyp
Publikováno v:
Journal of Allergy and Clinical Immunology. 139:21-28
The ability of lung imaging to phenotype patients, determine prognosis, and predict response to treatment is expanding in clinical and translational research. The purpose of this perspective is to describe current imaging modalities that might be use
Autor:
Benjamin Doyle, Clifford J. Woolf, Bruce P. Bean, Junwei Huang, David Roberson, Bruce D. Levy, Maryam Ahmadi, Simmie L. Foster, Sébastien Talbot, Liam E Browne, Jo-Chiao Wang, Ajay S. Yekkirala
Publikováno v:
J Allergy Clin Immunol
summary Airway sensory neuron-produced Substance P heightens allergy-induced goblet cell hyperplasia and hypersecretion of Muc5AC, electrically silencing these overreactive neurons reduced these components of lung type 2 allergic inflammatory respons
Autor:
Kaja Z. LeWinn, Nicole R. Bush, Terryl J. Hartman, Tebeb Gebretsadik, Kecia N. Carroll, Frances A. Tylavsky, Maria José Rosa, Paul E. Moore, Kourtney G. Gardner, Rosalind J. Wright, Robert Davis, Margaret A. Adgent
Publikováno v:
J Allergy Clin Immunol
The Journal of allergy and clinical immunology, vol 145, iss 3
The Journal of allergy and clinical immunology, vol 145, iss 3
BackgroundFindings on prenatal polyunsaturated fatty acid (PUFA) intake and child wheeze and asthma have been inconsistent.ObjectiveWe sought to examine associations between prenatal PUFA status and child wheeze/asthma and modifying effects of matern
Autor:
James E. Gern, Ronald E. Gangnon, Alex Thomas, Ronald L. Sorkness, Robert F. Lemanske, Daniel J. Jackson, Sean B. Fain, Michael D. Evans, Amy O. Thomas, Victoria Rajamanickam, Adesua Y. Okupa
Publikováno v:
Journal of Allergy and Clinical Immunology. 136:282-287
Background Sex influences the risk of wheezing illnesses and the prevalence of asthma throughout childhood. Objective To better understand the mechanisms of these effects, we analyzed longitudinal relationships between sex, lung physiology, and asthm
Publikováno v:
Journal of Allergy and Clinical Immunology. 134:554-559
The increased fraction of exhaled nitric oxide (Feno) values observed in asthmatic patients are thought to reflect increased airway inflammation. However, Feno values can be affected by airway caliber reduction, representing a bias when using Feno va