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Autor:
Joseph L. Baumert, Lyle C. Gurrin, Gillian DunnGalvin, Giovanni A. Zurzolo, Julie A. Nordlee, Jonathan O'b Hourihane, Katrina J. Allen, Wayne G. Shreffler, Steve L. Taylor, Audrey DunnGalvin
Publikováno v:
Journal of Allergy and Clinical Immunology. 139:1583-1590
Background: Eliciting doses (EDs) of allergenic foods can be defined by the distribution of threshold doses for subjects within a specific population. The ED05 is the dose that elicits a reaction in 5% of allergic subjects. The predicted ED05 for pea
Autor:
Stephen Pawsey, Charles W. Frankish, Roderick Peter Hafner, Kristen Armstrong, Mark W. Tenn, Anne K. Ellis, Lisa M. Steacy
Publikováno v:
Journal of Allergy and Clinical Immunology. 145:610-618.e9
Grass allergen peptides are in development for the treatment of grass pollen-induced allergic rhinoconjunctivitis. A previous randomized, placebo-controlled study demonstrated that grass allergen peptides significantly improved total rhinoconjunctivi
Autor:
Olivier de Beaumont, Hans-Jørgen Malling, Friedrich Horak, Alain Didier, Margitta Worm, Michel Melac, Gordon Sussman, Martine Le Gall
Publikováno v:
Journal of Allergy and Clinical Immunology. 128:559-566
Seasonal allergic rhinoconjunctivitis affects millions of persons. The efficacy of allergen sublingual immunotherapy (SLIT) was demonstrated in previous short-term studies.We sought to evaluate the sustained efficacy of 2 dosing regimens of a pre- an
Autor:
Siegfried Jäger, Michel Melac, Margitta Worm, Hans-Jørgen Malling, Alain Didier, A. Montagut, C. Andre, Friedrich Horak, Olivier de Beaumont
Publikováno v:
Journal of Allergy and Clinical Immunology. 120:1338-1345
Background Sublingual immunotherapy is well tolerated and data suggest its effectiveness for the treatment of allergic rhinitis in adults, but it lacks optimum dose definition. Objective To assess the efficacy, safety, and optimal dose of grass polle
Autor:
Joseph Scibilia, Carsten Bindslev-Jensen, Thomas Holzhauser, Barbara Ballmer-Weber, Diana Mittag, Claudio Ortolani, Morten Oesterballe, Guliana Zisa, Lars K. Poulsen, Stefan Vieths
Publikováno v:
Ballmer-Weber, B K, Holzhauser, T, Scibilia, J, Mittag, D, Zisa, G, Ortolani, C, Oesterballe, M, Poulsen, L K, Vieths, S & Bindslev-Jensen, C 2007, ' Clinical characteristics of soybean allergy in Europe : a double-blind, placebo-controlled food challenge study ', Journal of Allergy and Clinical Immunology, vol. 119, no. 6, pp. 1489-96 . https://doi.org/10.1016/j.jaci.2007.01.049
Udgivelsesdato: 2007-Jun BACKGROUND: Soybean is a relevant allergenic food, but little is known about individual threshold doses in soy allergy. OBJECTIVE: We sought to determine the clinical characteristics of soy allergy in Europe, including a dose
Autor:
Enrique Fernández-Caldas, Miguel Casanovas, José-Carlos García-Robaina, Fernando de la Torre, Inmaculada Sánchez
Publikováno v:
Journal of Allergy and Clinical Immunology. 118:1026-1032
Background Mite sensitivity is highly prevalent in tropical and subtropical regions, such as the Canary Islands. Objectives To evaluate the clinical efficacy and safety of a depigmented polymerized allergen vaccine containing a 50% mixture of Dermato
Autor:
Roy Gerth van Wijk, I. Terreehorst, A. J. Oosting, Marjolein S. de Bruin-Weller, Jan G.R. de Monchy, Carla A.F.M. Bruijnzeel-Koomen, Z. Tempels-Pavlica, Rob C. Aalberse
Publikováno v:
Journal of Allergy and Clinical Immunology, 110(3), 500-506. MOSBY-ELSEVIER
Journal of allergy and clinical immunology, 110(3), 500-506. Mosby Inc.
Journal of allergy and clinical immunology, 110(3), 500-506. Mosby Inc.
Background: House dust mite (HDM) allergen might induce and maintain atopic dermatitis (AD). Reduction of allergen load by applying encasings might improve the clinical symptoms of AD. Objective: We sought to investigate, in a randomized, double-blin
Publikováno v:
Journal of Allergy and Clinical Immunology. 109:777-783
Background: Birch pollen is a common allergen in northern, central, and eastern Europe. Earlier studies of specific immunotherapy using birch pollen extract were not placebo-controlled or were only preseasonal. Long-term, placebo-controlled studies w
Autor:
Stefan Zielen, Uwe Schauer, Michael Gräve, Wolfgang Leupold, Karl-Christian Bergmann, Ulrich Wahn, Wolfgang Kamin, Andrea von Berg, Claudia Rolinck-Werninghaus, Joachim Kuehr, Jens Brauburger, Thomas Hultsch
Publikováno v:
Journal of Allergy and Clinical Immunology. 109:274-280
Specific immunotherapy (SIT) and treatment with monoclonal anti-IgE antibody have complementary modes of action.The purpose of this study was to determine whether combined therapy could provide better efficacy than either treatment alone.We conducted
Autor:
Maria Angela Tosca, Florina Carat, C. Andre, Mario La Rosa, Giorgio Walter Canonica, Carmen Ranno
Publikováno v:
Journal of Allergy and Clinical Immunology. 104:425-432
Background: Sublingual-swallow immunotherapy was recently recognized in the World Health Organization Position Paper (Allergen immunotherapy: therapeutic vaccines for allergic diseases) “as a viable alternative to parenteral injection therapy to tr