Zobrazeno 1 - 10
of 441
pro vyhledávání: '"Nakanishi A"'
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(3):275-281
Publikováno v:
Japanese Journal of Pharmacology. 79:275-281
We investigated effects of a novel cardioprotective drug, JTV-519 (4-[3-(4-benzylpiperidin-1-yl)propionyl]-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine monohydrochloride) on membrane currents of guinea pig ventricular myocytes by whole-cell volta
Publikováno v:
Japanese Journal of Pharmacology. 78:269-278
Effects of YT-146 [2-(1-octynyl) adenosine], an adenosine A2 receptor agonist, on cAMP production and noradrenaline (NA) release were investigated in PC12 cells. YT-146 caused a concentration-dependent cAMP accumulation (EC50: 1.2±0.9 nM). In [3H]NA
Autor:
Takahiro Yokomakura, Yoko Aniya, Tomoyuki Koyama, Hisaharu Nakanishi, Masato Yonamine, Tatsumi Nagamine
Publikováno v:
Japanese Journal of Pharmacology. 72:175-181
Effect of acetaminophen on glutathione (GSH) S-transferase and related drug metabolizing ;nzymes was studied in vivo. Rats were given acetaminophen (250 mg/kg, i.p.) 24 hr after the treatment with 3-methylcholanthrene (25 mg/kg, i.p.) and killed by d
Publikováno v:
Japanese Journal of Pharmacology. 66:205-212
A confocal fluorescence microscope using fluo-3 and 9-(dicyanovinyl)- julolidine (DCVJ) was used to study the mast cell activation by the N-acetyl glucosamine oligomer specific lectin Datura stramonium agglutinin (DSA) and inhibition by antagonist le
Autor:
Tohru Masukawa, Kunio Nakanishi
Publikováno v:
Japanese Journal of Pharmacology. 63:279-284
The effects of disulfiram (DS) and its major metabolite, diethyldithiocarbamate (DEDC), on the survival time under normobaric and hypobaric hypoxia were examined in mice. At an ambient temperature of 24°C, DS at 0.5-3.0 mmol/kg (i.p.) caused a marke
Inhibitory Effect of NMDA on Dopaminergic Transmission in a Slice Preparation of Rat Globus Pallidus
Publikováno v:
Japanese Journal of Pharmacology. 58:79-82
The effect of N-methyl-D-aspartate (NMDA) on KCl-evoked endogenous dopamine (DA) release from slices of rat globus pallidus (GP) was examined. NMDA inhibited the KCl-evoked DA release in a dose-dependent manner. This inhibition was blocked by CPP, an
Publikováno v:
Japanese journal of pharmacology. 78(1)
Antioxidant and hepatoprotective actions of the mold Monascus anka (also called Beni-Koji in Japan) against acetaminophen (AAP)-induced liver toxicity were investigated. Serum aspartate aminotransferase and glutathione S-transferase (GST) activities
Publikováno v:
Japanese journal of pharmacology. 76(4)
Effects of nitric oxide (NO) synthase inhibitors on the enoxacin-induced convulsions were examined in mice pretreated with fenbufen. 7-Nitroindazole markedly suppressed the incidence of convulsions, whereas L -arginine did not modify the convulsions
Autor:
Suzuki, M. 1, Furuta, K. 1, Noyori, R. 2, Watanabe, Yu. 3, Matsumura, K. 3, Sato, T. 3, Ishikawa, T. 4, Nakanishi, M. 5, Långström, B. 6, Watanabe, Y. 3
Publikováno v:
In Japanese Journal of Pharmacology 1999 79 Supplement 1:20-20