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pro vyhledávání: ''
Autor:
Johanna C. Bendell, Katherine A. Guthrie, Charles D. Blanke, Jeffrey A. Meyerhardt, Pankaj Kumar, Eileen M. O'Reilly, Monica M. Bertagnolli, Jeffrey G. Meyer, Philip Kuebler, Félix Couture, Tyler Zemla, Alan P. Venook, Priya Kumthekar, Howard S. Hochster, Richard M. Goldberg, DeQuincy Andrew Lewis, Benjamin R. Tan, Charles S. Fuchs, Axel Grothey, Donna Niedzwiecki, Anthony F. Shields, Qian Shi
Publikováno v:
JAMA. 325(13)
Importance Aspirin and cyclooxygenase 2 (COX-2) inhibitors have been associated with a reduced risk of colorectal polyps and cancer in observational and randomized studies. The effect of celecoxib, a COX-2 inhibitor, as treatment for nonmetastatic co
Autor:
Sun, Eric, Mello, Michelle M., Rishel, Chris A., Vaughn, Michelle T., Kheterpal, Sachin, Saager, Leif, Fleisher, Lee A., Damrose, Edward J., Kadry, Bassam, Jena, Anupam B., Kooij, Fabian, Wilczak, Janet, Soto, Roy, Berris, Joshua, Price, Zachary, Urman, Richard D., Lins, Steven, Harris, John M., Cummings, Kenneth C., Berman, Mitchell F., Nanamori, Masakatsu, Adelman, Bruce T., Wedeven, Christopher, Bittner, Edward A., LaGorio, John, McCormick, Patrick J., Tom, Simon, Aziz, Michael F., Coffman, Traci, Ellis, Terri A., Molina, Susan, Peterson, William, Mackey, Sean C., van Klei, Wilton A., Mahajan, Aman, Jameson, Leslie C., Biggs, Daniel A., Neuman, Mark D., Craft, Robert M., Pace, Nathan L., Paganelli, William C., Durieux, Marcel E., Nair, Bala J., Wanderer, Jonathan P., Miller, Scott A., Helsten, Daniel L., Turnbull, Zachary A., Schonberger, Robert B.
Publikováno v:
JAMA-Journal of the American Medical Association, 321(8), 773. American Medical Association
Sun, E, Mello, M M, Rishel, C A, Vaughn, M T, Kheterpal, S, Saager, L, Fleisher, L A, Damrose, E J, Kadry, B, Jena, A B & Multicenter Perioperative Outcomes Group (MPOG) 2019, ' Association of Overlapping Surgery with Perioperative Outcomes ', JAMA-Journal of the American Medical Association, vol. 321, no. 8, pp. 762-772 . https://doi.org/10.1001/jama.2019.0711
JAMA, 321(8), 762-772. American Medical Association
JAMA-Journal of the American Medical Association, 321(8), 762-772. American Medical Association
Sun, E, Mello, M M, Rishel, C A, Vaughn, M T, Kheterpal, S, Saager, L, Fleisher, L A, Damrose, E J, Kadry, B, Jena, A B & Multicenter Perioperative Outcomes Group (MPOG) 2019, ' Association of Overlapping Surgery with Perioperative Outcomes ', JAMA-Journal of the American Medical Association, vol. 321, no. 8, pp. 762-772 . https://doi.org/10.1001/jama.2019.0711
JAMA, 321(8), 762-772. American Medical Association
JAMA-Journal of the American Medical Association, 321(8), 762-772. American Medical Association
Importance: Overlapping surgery, in which more than 1 procedure performed by the same primary surgeon is scheduled so the start time of one procedure overlaps with the end time of another, is of concern because of potential adverse outcomes. Objectiv
Autor:
Shorena Janelidze, Henrik Zetterberg, Sebastian Palmqvist, Antoine Leuzy, Nicholas K. Proctor, Ruben Smith, Diego Sepulveda-Falla, Eric M. Reiman, Yakeel T. Quiroz, Francisco Lopera, Geidy E. Serrano, Andrés Villegas, Thomas G. Beach, Oskar Hansson, Erik Stomrud, Xiyun Chai, Yinghua Chen, Olof Strandberg, Yi Su, Kaj Blennow, Niklas Mattsson-Carlgren, Jeffrey L. Dage
Publikováno v:
JAMA
IMPORTANCE: There are limitations in current diagnostic testing approaches for Alzheimer disease (AD). OBJECTIVE: To examine plasma tau phosphorylated at threonine 217 (P-tau217) as a diagnostic biomarker for AD. DESIGN, SETTING, AND PARTICIPANTS: Th
Autor:
Akira Kawai, Brian A. Van Tine, Javier Martin-Broto, Andrew J. Wagner, Albiruni Ryan Abdul Razak, Se Hoon Park, Yoichi Naito, Robin L. Jones, Patrick Schöffski, Jennifer Wright, William D. Tap, Chueh Chuan Yen, Victoria Soldatenkova, Axel Le Cesne, Ashwin Shahir, Gary Mo, Alexander I. Spira, Zsuzsanna Papai, Anders Krarup-Hansen, Kristen N. Ganjoo, Alexander Fedenko
Publikováno v:
JAMA
IMPORTANCE: Patients with advanced soft tissue sarcoma (STS) have a median overall survival of less than 2 years. In a phase 2 study, an overall survival benefit in this population was observed with the addition of olaratumab to doxorubicin over doxo
Publikováno v:
JAMA
Autor:
Sharukh Lokhandwala, Eric Yim, Francis X. Riedo, Maria Chong, Lindy Klaff, Matt Arentz, Melissa Lee
Publikováno v:
JAMA
This case series describes the clinical presentation, characteristics, and outcomes of patients with coronavirus disease 2019 (COVID-19) admitted to the intensive care unit at a public hospital in Washington State in February 2020, including initial
Publikováno v:
JAMA
This cohort study investigates whether the Sequential Organ Failure Assessment (SOFA) score is accurate enough to discriminate death from survival, and thus perhaps be a ventilator triage tool, for US patients with coronavirus disease 2019 (COVID-19)
Autor:
Christine R. West, Mark T. Brown, Dennis J. Levinson, Thomas J. Schnitzer, Shirley Pang, Lars Viktrup, Isabelle Davignon, Richard W. Easton, Glenn C. Pixton, Kenneth M. Verburg
Publikováno v:
JAMA. 322(1)
IMPORTANCE: Patients with osteoarthritis (OA) may remain symptomatic with traditional OA treatments. OBJECTIVE: To assess 2 subcutaneous tanezumab dosing regimens for OA. DESIGN, SETTING, AND PARTICIPANTS: A randomized, double-blind, multicenter tria
Autor:
Masashi Yoshida, Hironori Ohdaira, Masaki Kitajima, Shinya Okada, Mitsuyoshi Urashima, Yutaka Suzuki, Taisuke Akutsu
Publikováno v:
JAMA. 321(14)
IMPORTANCE: Randomized clinical trials of vitamin D supplementation for secondary prevention in patients with cancer are needed, given positive results of observational studies. OBJECTIVE: To determine whether postoperative vitamin D(3) supplementati
Autor:
Vasileios-Arsenios Lioutas, Tarikwa Leveille, Jose R. Romero, Hugo J. Aparicio, Jayandra J. Himali, Cristina S. Ivan, Sudha Seshadri, Alexa S. Beiser
Publikováno v:
JAMA
IMPORTANCE: Accurate estimation of the association between transient ischemic attack (TIA) and risk of subsequent stroke can help to improve preventive efforts and limit the burden of stroke in the population. OBJECTIVE: To determine population-based