Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Bonnie Ky"'
Autor:
Rachel Truitt, PhD, Anbin Mu, Elise A. Corbin, PhD, Alexia Vite, PhD, Jeffrey Brandimarto, PhD, Bonnie Ky, MD, MSCE, Kenneth B. Margulies, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 3, Iss 2, Pp 265-276 (2018)
Summary: Sunitinib, a multitargeted oral tyrosine kinase inhibitor, used widely to treat solid tumors, results in hypertension in up to 47% and left ventricular dysfunction in up to 19% of treated individuals. The relative contribution of afterload t
Externí odkaz:
https://doaj.org/article/8a7b6c28cc9d40ae987798036a3109ae
Autor:
Elizabeth W. Thompson, Biniyam G. Demissei, Amanda M. Smith, Priya Brahmbhatt, Jessica Wang, Amy Clark, Angela DeMichele, Vivek Narayan, Payal Shah, Lova Sun, Benedicte Lefebvre, Michael G. Fradley, Joseph R. Carver, W.H. Wilson Tang, Bonnie Ky
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • PON-1 is an HDL-associated cardioprotective enzyme that prevents oxidized-LDL formation and has not previously been studied in cardio-oncology. • To determine the associations between PON-1 and the development of
Highlights • PON-1 is an HDL-associated cardioprotective enzyme that prevents oxidized-LDL formation and has not previously been studied in cardio-oncology. • To determine the associations between PON-1 and the development of
Publikováno v:
JACC: Basic to Translational Science
Highlights • Cancer cells can promote metabolic remodeling in the heart. • Metabolic changes provide opportunities for novel treatment strategies to prevent heart failure and monitor disease progression through new imaging techniques. • Transla