Zobrazeno 1 - 10
of 300
pro vyhledávání: ''
Autor:
Christine E. Eyler, John A. Wolfgang, B. Noe, Nina N. Sanford, Clemens Grassberger, Kristy K. Brock, Theodore S. Hong, Jennifer Y. Wo, Jennifer Pursley, Issam El Naqa, Matthew Hwang, Beow Y. Yeap
Publikováno v:
Int J Radiat Oncol Biol Phys
Purpose This study aimed to develop robust normal-tissue complication probability (NTCP) models for patients with hepatocellular carcinoma treated with radiation therapy (RT) using Child-Pugh (CP) score and albumin-bilirubin (ALBI) grade increase as
Autor:
Catharine M L West, Lingjian Yang, Brian Lane, Joely J Irlam, Helen R Valentine, Yee Pei Song, Hitesh Mistry, Ananya Choudhury, Peter Hoskin
Publikováno v:
Song, Y P, Mistry, H, Irlam, J, Valentine, H, Yang, L, Lane, B, West, C, Choudhury, A & Hoskin, P J 2021, ' Long-Term Outcomes of Radical Radiation Therapy with Hypoxia Modification with Biomarker Discovery for Stratification: 10-Year Update of the BCON (Bladder Carbogen Nicotinamide) Phase 3 Randomized Trial (ISRCTN45938399) ', International Journal of Radiation: Oncology-Biology-Physics . https://doi.org/10.1016/j.ijrobp.2021.03.001
PurposeMany muscle-invasive bladder cancers are hypoxic, which limits the efficacy of radiation therapy. Hypoxia modification using carbogen and nicotinamide has been tested in a phase 3 trial, Bladder Carbogen Nicotinamide. We present mature follow-
Autor:
Bok Ai Choo, Nesaretnam Barr Kumarakulasinghe, Johann I. Tang, Valerie Heong, Mellisa Low, Diana Lim, Pearl Tong, Vicky Koh, Yi Wan Lim, Michelle Tseng, Siew Eng Lim, Jeffrey Low, Natalie Ngoi, David S.P. Tan, A. Ilancheran, Yee Liang Thian, Yiat Horng Leong, Joseph S. Ng
Publikováno v:
International journal of radiation oncology, biology, physics. 109(3)
Purpose Low-dose fractionated whole abdominal radiation therapy (LDFWART) has synergistic activity with paclitaxel in preclinical models. The aim of this phase 1 trial was to determine the recommended phase 2 dose and preliminary activity of weekly p
Autor:
Bridget F. Koontz, Patrick Healy, Karen E. Hoffman, Michael R. Harrison, Andrew J. Armstrong, Daniel J. George, Paul G. Corn, Susan Halabi, W. Robert Lee, Tian Zhang, Monika Anand, William R. Berry
Publikováno v:
International journal of radiation oncology, biology, physics. 109(5)
Long-term androgen-deprivation therapy (ADT) is the standard of care in combination with radiation therapy (RT) in high-risk prostate cancer (PC), despite substantial toxicity from the resulting hypogonadism. We hypothesized that a combination of mor
Autor:
Katerina Dedeckova, John Chang, Chirayu G. Patel, Pranshu Mohindra, Clayton B. Hess, John P. Plastaras, Christine E. Hill-Kayser, Nancy P. Mendenhall, Karen M. Winkfield, Yolanda D. Tseng, William F. Hartsell, Bradford S. Hoppe, L.R. Rosen, Raymond B. Mailhot Vega, Henry Tsai, Torunn I. Yock, Sujith Baliga, David M. Miller, Amit Maity
Publikováno v:
International journal of radiation oncology, biology, physics. 109(1)
Purpose Despite high response rates, there has been reluctance to use radiation therapy for patients with relapsed/refractory (r/r) Hodgkin (HL) or aggressive non-Hodgkin lymphoma (NHL) given concerns for subacute and late toxicities. Symptomatic pne
Publikováno v:
International journal of radiation oncology, biology, physics. 109(1)
Purpose We assessed the role of topical betamethasone as a prophylactic agent in patients receiving radiation for head and neck malignancies. Methods and Materials This randomized, open-label, phase 3 trial was completed at a single research institut
Autor:
Xiaofei Wang, Everett E. Vokes, James J. Urbanic, Lydia Hodgson, Thomas E. Stinchcombe, Jeffrey A. Bogart, Lyudmila Bazhenova, Steven E. Schild, Olwen Hahn, Ravi Salgia
Publikováno v:
International journal of radiation oncology, biology, physics, vol 101, iss 1
PurposeTo investigate the safety of accelerated hypofractionated radiation therapy (AHRT) with concurrent chemotherapy (CT) for inoperable stage III non-small cell lung cancer (NSCLC).Patients and methodsThe primary objectives were to define the maxi
Autor:
Allen M. Chen, Sophia Hsu, Megan E. Daly, John V. Hegde, Darlene Veruttipong, Narek Shaverdian, Carol Felix, Pin-Chieh Wang, Shyam Rao, Jonathan W. Riess
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 100:647-651
Purpose To analyze functional outcomes for patients treated on a phase 2 trial of de-escalated chemoradiation therapy for human papillomavirus–positive oropharyngeal cancer. Methods and Materials Patient eligibility included p16-positive, stage III
Autor:
Jose G. Bazan, Terence M. Williams, C. Barney, Ahmet S. Ayan, Gregory A. Otterson, Nicholas M. Scoville, E. Allan, Dominic DiCostanzo, John C. Grecula, Meng Xu-Welliver, K.E. Haglund
Publikováno v:
Int J Radiat Oncol Biol Phys
PURPOSE: To test the hypothesis that increasing radiation therapy (RT) dose to the thoracic vertebral bodies (TVBs) contributes to the development of hematologic toxicities (HTs) in patients with lung cancer. METHODS AND MATERIALS: Cases of non-small
Autor:
Victoria M. Villaflor, Everett E. Vokes, Ryan J. Brisson, Masha Kocherginsky, Tanguy Y. Seiwert, Mary Ellyn Witt, Apoorva Chawla, Daniel J. Haraf, Kerstin M. Stenson, Allison Dekker, Joseph K. Salama, Mark W. Lingen, Elizabeth A. Blair, J.M. Melotek, Ezra E.W. Cohen
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 96:21-29
The role of cetuximab in the treatment of locoregionally advanced head and neck squamous cell cancer (LA-HNSCC) remains poorly defined. In this phase 2 randomized study, we investigated the addition of cetuximab to both induction chemotherapy (IC) an