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Autor:
Nobuyuki Horita, Takahisa Eriguchi, Takeshi Kaneko, Naoko Sanuki, Yudai Tateishi, Atsuya Takeda, Yuichi Kibe, Yuichiro Tsurugai
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 111:143-151
Purpose We investigated whether delivery of a high biologically effective dose (BED) to primary tumors affects systemic outcomes of cancer-specific death (CSD) and overall survival (OS) rates after stereotactic body radiation therapy (SBRT) in patien
Autor:
Danielle S. Bitterman, Udo Hoffmann, Elizabeth H. Baldini, Anju Nohria, Raymond H. Mak, Katelyn M. Atkins, Hugo J.W.L. Aerts, Tafadzwa L. Chaunzwa, David Kozono, Balaji Tamarappoo
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 110:1473-1479
Mean heart dose (MHD) over 10 Gy and left anterior descending (LAD) coronary artery volume (V) receiving 15 Gy (V15Gy) greater than 10% can significantly increase the risk of major adverse cardiac events (MACE) in patients with non-small cell lung ca
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 110:438-443
Purpose The adrenal gland is a common site of metastasis in patients with advanced cancer, but it is rarely symptomatic. A subset of patients develop a complex pain syndrome with anorexia, nausea, and poorly localized visceral pain in the back, flank
Autor:
Hiromitsu Iwata, Misuzu Yoshihara, Toshiyuki Toshito, Eiji Kunii, Yusuke Yamaba, Kensuke Hayashi, Yuta Shibamoto, K. Nakajima, Y. Hattori, Hiroyuki Ogino, Kenji Akita, Osamu Takakuwa
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 109:1359-1367
Purpose This study prospectively evaluated the efficacy and safety of concurrent chemo-proton therapy (CCPT) using adaptive planning for unresectable stage III non-small cell lung cancer (NSCLC). Methods and Materials The primary endpoint was overall
Autor:
W. Zhu, Jiancheng Li, Xiaolong Fu, Luhua Wang, Baolin Qu, Ligang Xing, Jinming Yu, Conghua Xie, Chun Han, Zhengfei Zhu, Guang Li, Qin Lin, Yaping Xu, Zhiyong Yuan, Bing Lu, Tingyi Xia, Shenglin Ma, Gang Wu, Ming Chen, You Lu, Jianhua Wang, Guangying Zhu
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 109:1349-1358
Purpose This study aimed to compare erlotinib (E) and etoposide/cisplatin (EP) with concurrent radiation therapy (RT) for patients with stage IIIA/B unresectable advanced non-small cell lung cancer with activating epidermal growth factor receptor mut
Autor:
W David J Ryder, Catherine Harris, Stephen Harrow, Kate Haslett, Corinne Faivre-Finn, P. McCloskey, Matthew Hatton, Fiona McDonald, N. Bayman, Gerard G Hanna, N. Groom, Kevin Franks, Susan Harden
Publikováno v:
International Journal of Radiation Oncology, Biology, Physics
Haslett, K, Bayman, N, Franks, K, Groom, N, Harden, S V, Harris, C, Hanna, G, Harrow, S, Hatton, M, McCloskey, P, McDonald, F, Ryder, W D & Faivre-Finn, C 2021, ' Isotoxic Intensity Modulated Radiation Therapy in Stage III Non-Small Cell Lung Cancer: A Feasibility Study ', International Journal of Radiation Oncology Biology Physics, vol. 109, no. 5, pp. 1341-1348 . https://doi.org/10.1016/j.ijrobp.2020.11.040
Haslett, K, Bayman, N, Franks, K, Groom, N, Harden, S V, Harris, C, Hanna, G, Harrow, S, Hatton, M, McCloskey, P, McDonald, F, Ryder, W D & Faivre-Finn, C 2021, ' Isotoxic Intensity Modulated Radiation Therapy in Stage III Non-Small Cell Lung Cancer: A Feasibility Study ', International Journal of Radiation Oncology Biology Physics, vol. 109, no. 5, pp. 1341-1348 . https://doi.org/10.1016/j.ijrobp.2020.11.040
Purpose: Not all patients with stage III non-small cell lung cancer (NSCLC) are suitable for concurrent chemoradiation therapy (CRT). Local failure rate is high for sequential concurrent CRT. As such, there is a rationale for treatment intensificatio
Autor:
Gary D. Kao, Hongming Li, Yong Fan, Ying Xiao, Steven J. Feigenberg, Zhicheng Jiao, Charles B. Simone, Maya Galperin-Aizenberg, Charu Aggarwal, Daniel A. Pryma
Publikováno v:
Int J Radiat Oncol Biol Phys
Purpose To predict overall survival of patients receiving stereotactic body radiation therapy (SBRT) for early-stage non-small cell lung cancer (ES-NSCLC), we developed a radiomic model that integrates risk of death estimates and changes based on pre
Autor:
Alexander V. Louie, Liying Zhang, Patrick Cheung, Nauman Malik, Yee C. Ung, May Tsao, Georg A. Bjarnason, Ian Poon, Jeevin Shahi
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 109:764-774
Purpose Stereotactic body radiation therapy (SBRT) to metastatic mediastinal and hilar lymphadenopathy (MHL) is challenging owing to the proximity of centrally located organs-at-risk. As limited data exist on the safety and efficacy of SBRT for MHL,
Autor:
Biniyam G. Demissei, William P. Levin, Amit Maity, Abigail T. Berman, Keith A. Cengel, Sheela Krishnan, Bonnie Ky, Steven J. Feigenberg, Samuel Swisher-McClure, Gary M. Freedman, John P. Plastaras, Hari K. Narayan, Amanda M. Smith
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 109:946-952
The effects of thoracic radiation therapy (RT) on physical functioning and quality of life (QoL) are incompletely defined. We determined the associations between thoracic RT dose volume metrics, physical activity, and QoL in patients with cancer.Part
Autor:
Sungjune Kim, Kujtim Latifi, Gretchen MacMillan, Trevor Rose, Min-Hsuan Wang, Bradford A. Perez, Theresa A. Boyle, Scott J. Antonia, Jose R. Conejo-Garcia, Ahmad M. Karimi, Austin Lannon, Tawee Tanvetyanon, Jiannong Li, Eric B. Haura, Michael Shafique, Jhanelle E. Gray, Chase Powell, Stephen A. Rosenberg, G. Daniel Grass, Michael J. Schell, Thomas J. Dilling, Ben C. Creelan, Alberto Chiappori, James Saller, Andreas Saltos
Publikováno v:
Int J Radiat Oncol Biol Phys
Purpose Consolidative thoracic radiation therapy (TRT) has been shown to improve outcomes for patients with extensive stage small cell lung cancer. We hypothesized that the addition of ipilimumab (IPI) and nivolumab (NIVO) after TRT would improve out