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of 241
pro vyhledávání: ''
Autor:
Masahiko Murakami, Masafumi Takimoto, Midori Shida, Erica Yada, Takuya Tsunoda, Junji Tsurutani, Ryotaro Ohkuma, Nobuyuki Ohike, Satoshi Wada, Shinichi Kobayashi, Hirotsugu Ariizumi, Makoto Watanabe, Kiyoshi Yoshimura, Kazuyuki Hamada, Atsushi Horiike, Shumpei Ishikawa, Yutaro Kubota, Kiyohiro Ando, Tomoyuki Ishiguro, Daisuke Komura, Tomoko Norose, Yuya Hirasawa, Takeshi Aoki, Tetsuro Sasada, Rie Onoue
Publikováno v:
International Journal of Oncology
Pancreatic cancer is associated with an exceedingly poor prognosis, warranting the development of novel therapeutic strategies and discovery of prognostic predictors. Given that chemoresistance-related molecules are reportedly associated with the poo
Publikováno v:
International Journal of Oncology
Continuous human papillomavirus (HPV) infection is a critical cause of cervical lesions; however, the specific mechanism is currently not clear. E6 is one of the most important oncoproteins associated with HPV, which regulates synthases in the produc
Autor:
Daniel H. Palmer, John R. Arrand, Darren Barton, Wing Kin Syn, Nicholas D. James, Taha Elmetwali, Joseph J. Sacco, Puthen V. Jithesh, Richard M.D. Greensmith, D. Ross Sibson, Jawaher Ansari, Syed A. Hussain, Vijay Aachi, Bryony H. Lloyd
Publikováno v:
International Journal of Oncology
Despite advances in management, bladder cancer remains a major cause of cancer related complications. Characterisation of gene expression patterns in bladder cancer allows the identification of pathways involved in its pathogenesis, and may stimulate
Autor:
Keigo Hara, Daigo Ozawa, Tatsuya Miyazaki, Hiroyuki Kuwano, Yuji Kumakura, Makoto Sakai, Yuni Elsa Hadisaputri, Takehiko Yokobori, Hiroaki Honjo, Makoto Sohda
Publikováno v:
International Journal of Oncology. 50:1002-1010
Tumor necrosis factor α induced protein 3 (TNFAIP3) is a protein that is induced by TNF-mediated NF-κB activation and has a dual function in regulating NF-κB. TNFAIP3 is associated with inflammatory carcinogenesis in many cancer types. However, th
High Rab11-FIP4 expression predicts poor prognosis and exhibits tumor promotion in pancreatic cancer
Autor:
Yunfeng Shan, Yun He, Zhenzhai Cai, Mengsi Ye, Yu-Hui Zhou, Lingling Zhou, Zhan-Xiong Xue, Jinwei Zhong, Lu Guangrong, Jihang Zheng
Publikováno v:
International Journal of Oncology
Some studies have demonstrated that Rab11-family interacting proteins (Rab11-FIPs) are connected with the tumorigenesis, and they may act as tumor promoters in some cancers. The clinicopathological significance of Rab11-family interacting protein 4 (
Autor:
Takashi Okumura, Shin Takesue, Kenoki Ohuchida, Shigetaka Inoue, Akiko Yonenaga, Masafumi Nakamura, Kohei Nakata, Kazuhiro Koikawa, Kazuhiro Mizumoto, Akiko Sagara, Yohei Ando, Shin Kibe, Hiromichi Nakayama, Sho Endo, Koji Shido, Yoshihiro Miyasaka, Taiki Moriyama, Kei Miyoshi, Takao Ohtsuka, Toshiya Abe
Publikováno v:
International journal of oncology. 55(1)
Lymph node metastasis is an independent prognostic factor in pancreatic cancer. However, the mechanisms of lymph node colonization are unknown. As a mechanism of lymphatic metastasis, it has been reported for other types of cancer that spheroids from
Autor:
Bartłomiej Gałęcki, Donata Jarmołowska-Jurczyszyn, Andrzej Kluk, Hanna Drzewiecka, Paweł P. Jagodziński, Wojciech Dyszkiewicz
Publikováno v:
International Journal of Oncology
Numerous studies have reported that oestrogens may contribute to the development of non small cell lung cancer (NSCLC). Although different steroidogenic enzymes have been detected in the lung, the precise mechanism leading to an exaggerated accumulat
Autor:
Kouji Iida, Kohei Nakamura, Hiroshi Katagiri, Masako Ishikawa, Munmun Rahman, Emi Sato, Satoru Kyo, Kentaro Nakayama, Tomoka Ishibashi, Noriyuki Ishikawa, Mohammed Tanjimur Rahman
Publikováno v:
International Journal of Oncology
The clinicopathological significance of amplification was investigated of the gene encoding cyclin E (CCNE1) and we assessed whether CCNE1 was a potential target in endometrioid endometrial carcinomas. CCNE1 amplification and CCNE1 or F-box and WD re
Autor:
Renza Vento, Luca Cicalese, Mahmoud A. Eltorky, Cristiana Rastellini, Xiaofu Wang, Mauro Montalbano, Tiziana Corsello
Publikováno v:
International Journal of Oncology. 48:1205-1217
Hepatocellular carcinoma (HCC) is the most common primary liver cancer. Currently, there is limited knowledge of neoplastic transformation of hepatocytes in HCC. In clinical practice, the high rate of HCC local recurrence suggests the presence of dif
Autor:
Fuyou Zhao, Shukui Qin, Yan Yang, Yu Zhao, Yurong Ou, Jian Zhu, Qiong Wu, Wanyun Li, Na Zhang
Publikováno v:
International Journal of Oncology. 48:703-713
Hepatocellular carcinoma (HCC) is generally believed to have low sensitivity to chemotherapeutic agents including oxaliplatin (OXA). Studies have demonstrated that gap junctions (GJs) composed of connexin (Cx) proteins have the potential to modulate