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Autor:
Keigo Hara, Daigo Ozawa, Tatsuya Miyazaki, Hiroyuki Kuwano, Yuji Kumakura, Makoto Sakai, Yuni Elsa Hadisaputri, Takehiko Yokobori, Hiroaki Honjo, Makoto Sohda
Publikováno v:
International Journal of Oncology. 50:1002-1010
Tumor necrosis factor α induced protein 3 (TNFAIP3) is a protein that is induced by TNF-mediated NF-κB activation and has a dual function in regulating NF-κB. TNFAIP3 is associated with inflammatory carcinogenesis in many cancer types. However, th
Autor:
Fuyou Zhao, Shukui Qin, Yan Yang, Yu Zhao, Yurong Ou, Jian Zhu, Qiong Wu, Wanyun Li, Na Zhang
Publikováno v:
International Journal of Oncology. 48:703-713
Hepatocellular carcinoma (HCC) is generally believed to have low sensitivity to chemotherapeutic agents including oxaliplatin (OXA). Studies have demonstrated that gap junctions (GJs) composed of connexin (Cx) proteins have the potential to modulate
Autor:
Nichapavee Nutthasirikul, Siri Chau-in, Anchalee Techasen, Temduang Limpaiboon, Chanvit Leelayuwat, Chariya Hahnvajanawong, Patcharee Jearanaikoon
Publikováno v:
International Journal of Oncology. 47:2153-2164
Lack of the normal p53 transactivation domain, A¢ÂÂ133p53 isoform exhibits anti-p53 function. Many studies report the correlation between A¢ÂÂ133p53 expression and poor survival in various cancers, including cholangiocarcinoma (CCA), wh
Autor:
Xiulong Zhang, Xinmiao Yang, Jie Fu, Weiwei Yu, Xiaojing Yang, Hanru Ren, Yi Sun, Yuhui Shao, Hongling Li, Lihua Zhang
Publikováno v:
International journal of oncology. 52(6)
The chaperonin-containing T‑complex protein 1 (CCT) has eight subunits, CCT 1-8, which are dysregulated in several types of cancer. To determine how subunit 8 (CCT8) influences the development of esophageal squamous cell carcinoma (ESCC), immunohis
Publikováno v:
International Journal of Oncology. 47:1503-1511
The high-mobility group nucleosome-binding protein-5 (HMGN5) is frequently overexpressed in various malignant cancers. However, the potential correlation between HMGN5 and prognosis in patients with meningiomas remains unknown. In the present study,
Autor:
Norihiko Tokuzen, Satoshi Hino, Hiroyuki Hamakawa, Hiroshi Tanaka, Jun Onodera, Shingo Hara, Ichiro Fujimoto, Kazuki Iwamoto, Koh-ichi Nakashiro, Hiroyuki Goda
Publikováno v:
International Journal of Oncology. 47:1273-1281
Oncogene addiction can provide therapeutic opportunities in human malignancies. In this study, we aimed to identify critical oncogenes for oral squamous cell carcinoma (OSCC) development and progression. We determined gene expression profiles in 10 p
Publikováno v:
International Journal of Oncology. 45:1547-1555
Cell division cycle 20 (CDC20) encodes a regulatory protein interacting with the anaphase-promoting complex/cyclosome (APC/C) in the cell cycle and plays important roles in tumorigenesis and progression of multiple tumors. The present study aimed to
Autor:
Norihiko Yamamoto, Ryuji Okamoto, Masahiko Tameda, Takahiro Kojima, Tsutomu Nobori, Hideaki Suzuki, Masanobu Usui, Kazushi Sugimoto, Yoshiyuki Takei, Masaaki Ito, Kazuhiko Uchida, Masako Uchida, Katsuya Shiraki
Publikováno v:
International Journal of Oncology
Although several therapeutic options are available for hepatocellular carcinoma (HCC), the outcome is still very poor. One reason is the complexity of signal transduction in the pathogenesis of HCC. The aim of this study was to iden- tify new HCC-rel
Publikováno v:
International Journal of Oncology. 45:273-281
The aim of the present study was to evaluate the expression and localization of connexin (Cx) 26, -43 and -45 in a group of 35 patients with primary oral squamous cell carci- noma (OSCC) with the objective of making a more accurate disease prognosis.
Publikováno v:
International Journal of Oncology
Keratinocyte growth factor (KGF), also known as fibroblast growth factor-7, and KGF receptor (KGFR) play important roles in the growth of epithelial cells and are overexpressed in a variety of malignant epithelial tumors, including pancreatic ductal