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Publikováno v:
International Journal of Oncology
Primary central nervous system lymphoma (PCNSL) is a rare subtype of extranodal non‑Hodgkin lymphoma that is unique and different from systemic diffuse large B‑cell lymphomas. The median age at diagnosis of PCNSL is 65 years and its incidence is
Autor:
Shangzhi Xie, Xiao-Rui Luan, J. Zhang, Xiaoxiao Zheng, Hai-Ping Ke, Ke Chen, Rong-Rong Liu, Wei Chen, Xian-Ning Zhang, Yuexiao Tang
Publikováno v:
International Journal of Oncology
Hepatocellular carcinoma (HCC) is an invasive malignant neoplasm with a poor prognosis. The development of chemoresistance severely obstructs the chemotherapeutic efficiency of HCC treatment. Therefore, understanding the mechanisms of chemoresistance
Autor:
Minglei Li, Heng Song, Lingxiao Xing, Xianghong Zhang, Xiaosong Ding, Haitao Shen, Yuehong Li, Hui Li
Publikováno v:
International Journal of Oncology
Long non‑coding RNAs (lncRNAs) have emerged as key players in the development and progression of cancer. FEZ family zinc finger 1 antisense RNA 1 (FEZF1‑AS1) is a novel lncRNA that is involved in the development of cancer and acts as a potential
Publikováno v:
International Journal of Oncology
Accumulating evidence suggests that inflammation is present in solid tumors. However, it is poorly understood whether inflammation exists in glioma and how it affects the metabolic signature of glioma. By analyzing immunohistochemical data and gene e
Autor:
Ina Bähr, Lina Jaeschke, Katharina Nimptsch, Jürgen Janke, Pia Herrmann, Dennis Kobelt, Heike Kielstein, Tobias Pischon, Ulrike Stein
Publikováno v:
International Journal of Oncology
Obesity is a major and increasing public health concern, associated with an increased risk of and mortality from several types of cancer including colorectal cancer (CRC), being associated with cancer progression, metastasis and resistance to therapy
Publikováno v:
International Journal of Oncology
Circular RNAs (circRNAs) are non‑coding RNAs that are connected at the 3' and 5' ends by an exon or intron. Studies increasingly show that circRNAs play an important role in tumorigenesis by acting as a 'sponge' for microRNAs (miRNAs), which abroga
Publikováno v:
International Journal of Oncology
MicroRNA-301a (miRNA/miR-301a) and nuclear factor (NF)-κB signaling play important roles in tumor invasion, migration and progression. However, the role of miRNA-301a-3p in human gastric cancer (GC), and specifically in the activation of NF-κB sign
Publikováno v:
International Journal of Oncology
Spinal metastasis occurs in 50-75% of bone metastases caused by hepatocellular carcinoma (HCC), and HCC-derived spinal metastasis can lead to a less favorable prognosis. Recently, several studies have demonstrated that C-X3-C motif chemokine ligand 1
Autor:
Gongxian Wang, Yuanyuan Lin, An Xie, Weipeng Liu, Feng Yu, Yi Zheng, Dan Tang, Xiaochen Zhou, Xinping Xu
Publikováno v:
International Journal of Oncology
Prostate cancer (PCa) is the second leading cause of cancer related death among men worldwide. The present study aimed to investigate the role of germ cell-specific gene 2 protein (GSG2), also termed histone H3 phosphorylated by GSG2 at threonine 3,
Publikováno v:
International Journal of Oncology
Hepatocellular carcinoma (HCC) is one of the most malignant types of cancer, and is associated with high recurrence rates and a poor response to chemotherapy. Immune signatures in the microenvironment of HCC have not been well explored systematically